STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBE2WUBIQUITIN_CONJUGAT_2 domain-containing protein. (179 aa)    
Predicted Functional Partners:
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
   
 0.983
TRIP12
Thyroid hormone receptor interactor 12.
   
 0.895
UBE2J1
Ubiquitin conjugating enzyme E2 J1.
   
 
 0.894
UBA1
Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (By similarity).
   
 0.879
FANCL
FA complementation group L.
   
 0.877
LOC100344152
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.873
UBE2H
Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.850
UBE2K
Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.
     
0.761
UBE2J2
Ubiquitin conjugating enzyme E2 J2.
    
 0.759
ATXN3
Josephin domain-containing protein.
    
 
 0.749
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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