| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATXN3 | UBA1 | ENSOCUP00000004940 | ENSOCUP00000007237 | Josephin domain-containing protein. | Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (By similarity). | 0.472 |
| ATXN3 | UBE2W | ENSOCUP00000004940 | ENSOCUP00000008834 | Josephin domain-containing protein. | UBIQUITIN_CONJUGAT_2 domain-containing protein. | 0.749 |
| FANCL | TRIP12 | ENSOCUP00000049943 | ENSOCUP00000034286 | FA complementation group L. | Thyroid hormone receptor interactor 12. | 0.648 |
| FANCL | UBE2W | ENSOCUP00000049943 | ENSOCUP00000008834 | FA complementation group L. | UBIQUITIN_CONJUGAT_2 domain-containing protein. | 0.877 |
| LOC100344152 | UBA1 | ENSOCUP00000005992 | ENSOCUP00000007237 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (By similarity). | 0.705 |
| LOC100344152 | UBE2H | ENSOCUP00000005992 | ENSOCUP00000042107 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. | 0.697 |
| LOC100344152 | UBE2J1 | ENSOCUP00000005992 | ENSOCUP00000004584 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | Ubiquitin conjugating enzyme E2 J1. | 0.743 |
| LOC100344152 | UBE2J2 | ENSOCUP00000005992 | ENSOCUP00000000835 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | Ubiquitin conjugating enzyme E2 J2. | 0.639 |
| LOC100344152 | UBE2K | ENSOCUP00000005992 | ENSOCUP00000005089 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. | 0.714 |
| LOC100344152 | UBE2W | ENSOCUP00000005992 | ENSOCUP00000008834 | UBIQUITIN_CONJUGAT_2 domain-containing protein. | UBIQUITIN_CONJUGAT_2 domain-containing protein. | 0.873 |
| TRIP12 | FANCL | ENSOCUP00000034286 | ENSOCUP00000049943 | Thyroid hormone receptor interactor 12. | FA complementation group L. | 0.648 |
| TRIP12 | UBA1 | ENSOCUP00000034286 | ENSOCUP00000007237 | Thyroid hormone receptor interactor 12. | Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (By similarity). | 0.976 |
| TRIP12 | UBE2H | ENSOCUP00000034286 | ENSOCUP00000042107 | Thyroid hormone receptor interactor 12. | Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family. | 0.743 |
| TRIP12 | UBE2J1 | ENSOCUP00000034286 | ENSOCUP00000004584 | Thyroid hormone receptor interactor 12. | Ubiquitin conjugating enzyme E2 J1. | 0.752 |
| TRIP12 | UBE2J2 | ENSOCUP00000034286 | ENSOCUP00000000835 | Thyroid hormone receptor interactor 12. | Ubiquitin conjugating enzyme E2 J2. | 0.560 |
| TRIP12 | UBE2K | ENSOCUP00000034286 | ENSOCUP00000005089 | Thyroid hormone receptor interactor 12. | Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. | 0.958 |
| TRIP12 | UBE2V1 | ENSOCUP00000034286 | ENSOCUP00000016545 | Thyroid hormone receptor interactor 12. | Ubiquitin conjugating enzyme E2 V1. | 0.435 |
| TRIP12 | UBE2W | ENSOCUP00000034286 | ENSOCUP00000008834 | Thyroid hormone receptor interactor 12. | UBIQUITIN_CONJUGAT_2 domain-containing protein. | 0.895 |
| UBA1 | ATXN3 | ENSOCUP00000007237 | ENSOCUP00000004940 | Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (By similarity). | Josephin domain-containing protein. | 0.472 |
| UBA1 | LOC100344152 | ENSOCUP00000007237 | ENSOCUP00000005992 | Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (By similarity). | UBIQUITIN_CONJUGAT_2 domain-containing protein. | 0.705 |