Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TMEM106BTransmembrane protein 106B. (275 aa)    
Predicted Functional Partners:
GRN
Granulin precursor.
   
  
 0.834
C9orf72
C9orf72-SMCR8 complex subunit.
      
 0.795
CHMP2B
Charged multivesicular body protein 2B.
   
 
 0.760
TMEM239
Uncharacterized protein.
      
 0.702
PSAP
Prosaposin.
   
  
 0.655
TMEM41B
Transmembrane protein 41B.
   
  
 0.638
MAPT
Microtubule-associated protein.
    
 
 0.623
SORT1
Sortilin.
   
  
 0.617
LMAN2
Lectin, mannose binding 2.
    
 
 0.604
LAMP1
Lysosomal associated membrane protein 1.
    
 
 0.597
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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