Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SIPA1L2Signal induced proliferation associated 1 like 2. (1719 aa)    
Predicted Functional Partners:
RAP1A
Uncharacterized protein.
    
 0.867
RAP1B
Uncharacterized protein.
    
 0.821
PRR35
Proline rich 35.
      
 0.812
KBTBD12
Kelch repeat and BTB domain containing 12.
     
 0.797
ENSOCUP00000038019
Uncharacterized protein.
    
 0.782
RRP36
Ribosomal RNA processing 36.
      
 0.769
CCDC36
Coiled-coil domain containing 36.
      
 0.768
TOGARAM1
TOG array regulator of axonemal microtubules 1.
   
  
 0.732
AFDN
Afadin, adherens junction formation factor.
   
 0.708
LZTS1
Leucine zipper tumor suppressor 1.
    
 
 0.703
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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