| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALOX12 | ALOX15B | ENSOCUP00000024211 | ENSOCUP00000008906 | Arachidonate 12-lipoxygenase, 12S type. | Arachidonate 15-lipoxygenase type B. | 0.875 |
| ALOX12 | PLA2G3 | ENSOCUP00000024211 | ENSOCUP00000003567 | Arachidonate 12-lipoxygenase, 12S type. | Phospholipase A2 group III. | 0.868 |
| ALOX12 | PLA2G4A | ENSOCUP00000024211 | ENSOCUP00000012590 | Arachidonate 12-lipoxygenase, 12S type. | Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (By similarity). | 0.858 |
| ALOX12 | PLA2G4B | ENSOCUP00000024211 | ENSOCUP00000010309 | Arachidonate 12-lipoxygenase, 12S type. | Phospholipase A2. | 0.859 |
| ALOX12 | PLA2G4C | ENSOCUP00000024211 | ENSOCUP00000012869 | Arachidonate 12-lipoxygenase, 12S type. | PLA2c domain-containing protein. | 0.851 |
| ALOX12 | PLA2G4D | ENSOCUP00000024211 | ENSOCUP00000012034 | Arachidonate 12-lipoxygenase, 12S type. | Phospholipase A2. | 0.853 |
| ALOX12 | PLA2G4E | ENSOCUP00000024211 | ENSOCUP00000032066 | Arachidonate 12-lipoxygenase, 12S type. | Phospholipase A2. | 0.855 |
| ALOX12 | PLA2G4F | ENSOCUP00000024211 | ENSOCUP00000034665 | Arachidonate 12-lipoxygenase, 12S type. | Phospholipase A2. | 0.853 |
| ALOX12 | PTGS1 | ENSOCUP00000024211 | ENSOCUP00000031756 | Arachidonate 12-lipoxygenase, 12S type. | Prostaglandin G/H synthase 1; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells (By similarity). | 0.884 |
| ALOX12 | PTGS2 | ENSOCUP00000024211 | ENSOCUP00000014415 | Arachidonate 12-lipoxygenase, 12S type. | Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] | 0.859 |
| ALOX15B | ALOX12 | ENSOCUP00000008906 | ENSOCUP00000024211 | Arachidonate 15-lipoxygenase type B. | Arachidonate 12-lipoxygenase, 12S type. | 0.875 |
| ALOX15B | PLA2G3 | ENSOCUP00000008906 | ENSOCUP00000003567 | Arachidonate 15-lipoxygenase type B. | Phospholipase A2 group III. | 0.876 |
| ALOX15B | PLA2G4A | ENSOCUP00000008906 | ENSOCUP00000012590 | Arachidonate 15-lipoxygenase type B. | Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (By similarity). | 0.908 |
| ALOX15B | PLA2G4B | ENSOCUP00000008906 | ENSOCUP00000010309 | Arachidonate 15-lipoxygenase type B. | Phospholipase A2. | 0.918 |
| ALOX15B | PLA2G4C | ENSOCUP00000008906 | ENSOCUP00000012869 | Arachidonate 15-lipoxygenase type B. | PLA2c domain-containing protein. | 0.921 |
| ALOX15B | PLA2G4D | ENSOCUP00000008906 | ENSOCUP00000012034 | Arachidonate 15-lipoxygenase type B. | Phospholipase A2. | 0.920 |
| ALOX15B | PLA2G4E | ENSOCUP00000008906 | ENSOCUP00000032066 | Arachidonate 15-lipoxygenase type B. | Phospholipase A2. | 0.914 |
| ALOX15B | PLA2G4F | ENSOCUP00000008906 | ENSOCUP00000034665 | Arachidonate 15-lipoxygenase type B. | Phospholipase A2. | 0.924 |
| ALOX15B | PTGS1 | ENSOCUP00000008906 | ENSOCUP00000031756 | Arachidonate 15-lipoxygenase type B. | Prostaglandin G/H synthase 1; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells (By similarity). | 0.884 |
| ALOX15B | PTGS2 | ENSOCUP00000008906 | ENSOCUP00000014415 | Arachidonate 15-lipoxygenase type B. | Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] | 0.887 |
