STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SH3BP5SH3 domain binding protein 5. (454 aa)    
Predicted Functional Partners:
RAB11B
Ras-related protein Rab-11A; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The small Rab GTPase RAB11A regulates endocytic recycling. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial c [...]
    
 
 0.844
DHPS
Uncharacterized protein.
      
 0.774
RAB11A
Oryctolagus cuniculus RAB11A, member RAS oncogene family (RAB11A), mRNA.
   
 
 0.765
TRAPPC10
Uncharacterized protein.
   
  
 0.758
PNKD
PNKD metallo-beta-lactamase domain containing.
   
  
 0.736
ATP2B4
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.
      
 0.670
METTL6
Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family.
 
      0.629
PRCP
Prolylcarboxypeptidase.
      
 0.626
TRAPPC11
Trafficking protein particle complex 11.
      
 0.619
PRRC2B
Proline rich coiled-coil 2B.
   
  
 0.613
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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