STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPR3Natriuretic peptide receptor 3. (536 aa)    
Predicted Functional Partners:
NPPA
Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity); Belongs to the natriuretic peptide family.
    
 0.969
NPPC
Uncharacterized protein.
    
 0.968
G1SLG9_RABIT
Uncharacterized protein.
    
 0.909
NPPB
Uncharacterized protein.
    
 0.909
GUCA2B
Uncharacterized protein.
   
 
 0.745
GUCA2A
Guanylate cyclase activator 2A.
   
 
 0.745
GAK
Cyclin G associated kinase.
      
 0.497
NPTXR
Neuronal pentraxin receptor.
      
 0.424
GAD2
Glutamate decarboxylase 2.
     
 0.422
GUCY2C
Guanylate cyclase.
 
  
 
0.413
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: medium (48%) [HD]