node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADIPOQ | APOA1 | ENSOCUP00000020897 | ENSOCUP00000009241 | C1q domain-containing protein. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | 0.424 |
ADIPOQ | CRP | ENSOCUP00000020897 | ENSOCUP00000004059 | C1q domain-containing protein. | C-reactive protein; Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity). | 0.766 |
ADIPOQ | RBP4 | ENSOCUP00000020897 | ENSOCUP00000009070 | C1q domain-containing protein. | Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. | 0.639 |
ADIPOQ | RETN | ENSOCUP00000020897 | ENSOCUP00000019254 | C1q domain-containing protein. | Resistin. | 0.955 |
AHSG | APOA1 | ENSOCUP00000026521 | ENSOCUP00000009241 | Alpha-2-HS-glycoprotein; A cell adhesion protein that binds immature cells of the granulocyte lineage; Belongs to the fetuin family. | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | 0.812 |
AHSG | CRP | ENSOCUP00000026521 | ENSOCUP00000004059 | Alpha-2-HS-glycoprotein; A cell adhesion protein that binds immature cells of the granulocyte lineage; Belongs to the fetuin family. | C-reactive protein; Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity). | 0.542 |
AHSG | GC | ENSOCUP00000026521 | ENSOCUP00000047639 | Alpha-2-HS-glycoprotein; A cell adhesion protein that binds immature cells of the granulocyte lineage; Belongs to the fetuin family. | Vitamin D-binding protein; Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. | 0.916 |
AHSG | RBP4 | ENSOCUP00000026521 | ENSOCUP00000009070 | Alpha-2-HS-glycoprotein; A cell adhesion protein that binds immature cells of the granulocyte lineage; Belongs to the fetuin family. | Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. | 0.671 |
AHSG | TTR | ENSOCUP00000026521 | ENSOCUP00000014907 | Alpha-2-HS-glycoprotein; A cell adhesion protein that binds immature cells of the granulocyte lineage; Belongs to the fetuin family. | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). Belongs to the transthyretin family. | 0.756 |
APOA1 | ADIPOQ | ENSOCUP00000009241 | ENSOCUP00000020897 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | C1q domain-containing protein. | 0.424 |
APOA1 | AHSG | ENSOCUP00000009241 | ENSOCUP00000026521 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | Alpha-2-HS-glycoprotein; A cell adhesion protein that binds immature cells of the granulocyte lineage; Belongs to the fetuin family. | 0.812 |
APOA1 | CRP | ENSOCUP00000009241 | ENSOCUP00000004059 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | C-reactive protein; Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity). | 0.775 |
APOA1 | G1TFX3_RABIT | ENSOCUP00000009241 | ENSOCUP00000015820 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | 5-hydroxyisourate hydrolase; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.442 |
APOA1 | GC | ENSOCUP00000009241 | ENSOCUP00000047639 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | Vitamin D-binding protein; Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. | 0.685 |
APOA1 | RBP4 | ENSOCUP00000009241 | ENSOCUP00000009070 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | Retinol-binding protein 4; Retinol-binding protein that mediates retinol transport in blood plasma. Delivers retinol from the liver stores to the peripheral tissues. Transfers the bound all-trans retinol to STRA6, that then facilitates retinol transport across the cell membrane. | 0.611 |
APOA1 | TTR | ENSOCUP00000009241 | ENSOCUP00000014907 | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). Belongs to the transthyretin family. | 0.937 |
CRP | ADIPOQ | ENSOCUP00000004059 | ENSOCUP00000020897 | C-reactive protein; Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity). | C1q domain-containing protein. | 0.766 |
CRP | AHSG | ENSOCUP00000004059 | ENSOCUP00000026521 | C-reactive protein; Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity). | Alpha-2-HS-glycoprotein; A cell adhesion protein that binds immature cells of the granulocyte lineage; Belongs to the fetuin family. | 0.542 |
CRP | APOA1 | ENSOCUP00000004059 | ENSOCUP00000009241 | C-reactive protein; Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity). | Truncated apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. | 0.775 |
CRP | GC | ENSOCUP00000004059 | ENSOCUP00000047639 | C-reactive protein; Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells (By similarity). | Vitamin D-binding protein; Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. | 0.498 |