ERBB2 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

ERBB2

Receptor protein-tyrosine kinase. (1255 aa)

Predicted Functional Partners:

EGFR

0.999

ERBB3

0.999

NRG1

0.999

EGF

0.998

ERBB4

0.998

GRB2

0.997

SHC1

0.995

TGFA

0.993

PIK3CA

0.991

ERBIN

0.990

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGF	EGFR	ENSOCUP00000014095	ENSOCUP00000009041	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.999
EGF	ERBB2	ENSOCUP00000014095	ENSOCUP00000009117	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.998
EGF	ERBB3	ENSOCUP00000014095	ENSOCUP00000014890	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Erb-b2 receptor tyrosine kinase 3.	0.998
EGF	ERBB4	ENSOCUP00000014095	ENSOCUP00000035750	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Receptor protein-tyrosine kinase.	0.997
EGF	GRB2	ENSOCUP00000014095	ENSOCUP00000042433	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Growth factor receptor bound protein 2.	0.930
EGF	NRG1	ENSOCUP00000014095	ENSOCUP00000033862	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Neuregulin 1.	0.891
EGF	PIK3CA	ENSOCUP00000014095	ENSOCUP00000026298	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.772
EGF	SHC1	ENSOCUP00000014095	ENSOCUP00000013916	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	SHC adaptor protein 1.	0.709
EGF	TGFA	ENSOCUP00000014095	ENSOCUP00000035430	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	Transforming growth factor alpha; TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar (By similarity). Inhibitor of acid secretion. Inhibitor of aminopyrine uptake in parietal cells (in vitro).	0.983
EGFR	EGF	ENSOCUP00000009041	ENSOCUP00000014095	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.999
EGFR	ERBB2	ENSOCUP00000009041	ENSOCUP00000009117	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.999
EGFR	ERBB3	ENSOCUP00000009041	ENSOCUP00000014890	Receptor protein-tyrosine kinase.	Erb-b2 receptor tyrosine kinase 3.	0.998
EGFR	ERBB4	ENSOCUP00000009041	ENSOCUP00000035750	Receptor protein-tyrosine kinase.	Receptor protein-tyrosine kinase.	0.944
EGFR	ERBIN	ENSOCUP00000009041	ENSOCUP00000003295	Receptor protein-tyrosine kinase.	Erbb2 interacting protein.	0.605
EGFR	GRB2	ENSOCUP00000009041	ENSOCUP00000042433	Receptor protein-tyrosine kinase.	Growth factor receptor bound protein 2.	0.999
EGFR	NRG1	ENSOCUP00000009041	ENSOCUP00000033862	Receptor protein-tyrosine kinase.	Neuregulin 1.	0.995
EGFR	PIK3CA	ENSOCUP00000009041	ENSOCUP00000026298	Receptor protein-tyrosine kinase.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.998
EGFR	SHC1	ENSOCUP00000009041	ENSOCUP00000013916	Receptor protein-tyrosine kinase.	SHC adaptor protein 1.	0.999
EGFR	TGFA	ENSOCUP00000009041	ENSOCUP00000035430	Receptor protein-tyrosine kinase.	Transforming growth factor alpha; TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar (By similarity). Inhibitor of acid secretion. Inhibitor of aminopyrine uptake in parietal cells (in vitro).	0.999
ERBB2	EGF	ENSOCUP00000009117	ENSOCUP00000014095	Receptor protein-tyrosine kinase.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.998