| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DUSP1 | FOS | ENSOCUP00000006912 | ENSOCUP00000021434 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Fos proto-oncogene, AP-1 transcription factor subunit. | 0.897 |
| DUSP1 | JUN | ENSOCUP00000006912 | ENSOCUP00000040325 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | BZIP domain-containing protein; Belongs to the bZIP family. | 0.879 |
| DUSP1 | MAP2K7 | ENSOCUP00000006912 | ENSOCUP00000017722 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Mitogen-activated protein kinase kinase 7. | 0.420 |
| DUSP1 | MAPK10 | ENSOCUP00000006912 | ENSOCUP00000009184 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Mitogen-activated protein kinase. | 0.962 |
| DUSP1 | MAPK9 | ENSOCUP00000006912 | ENSOCUP00000031059 | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | Mitogen-activated protein kinase. | 0.951 |
| FOS | DUSP1 | ENSOCUP00000021434 | ENSOCUP00000006912 | Fos proto-oncogene, AP-1 transcription factor subunit. | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.897 |
| FOS | JUN | ENSOCUP00000021434 | ENSOCUP00000040325 | Fos proto-oncogene, AP-1 transcription factor subunit. | BZIP domain-containing protein; Belongs to the bZIP family. | 0.999 |
| FOS | MAPK10 | ENSOCUP00000021434 | ENSOCUP00000009184 | Fos proto-oncogene, AP-1 transcription factor subunit. | Mitogen-activated protein kinase. | 0.968 |
| FOS | MAPK9 | ENSOCUP00000021434 | ENSOCUP00000031059 | Fos proto-oncogene, AP-1 transcription factor subunit. | Mitogen-activated protein kinase. | 0.976 |
| FOS | TP53 | ENSOCUP00000021434 | ENSOCUP00000000989 | Fos proto-oncogene, AP-1 transcription factor subunit. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.657 |
| JUN | DUSP1 | ENSOCUP00000040325 | ENSOCUP00000006912 | BZIP domain-containing protein; Belongs to the bZIP family. | Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. | 0.879 |
| JUN | FOS | ENSOCUP00000040325 | ENSOCUP00000021434 | BZIP domain-containing protein; Belongs to the bZIP family. | Fos proto-oncogene, AP-1 transcription factor subunit. | 0.999 |
| JUN | MAP2K4 | ENSOCUP00000040325 | ENSOCUP00000035427 | BZIP domain-containing protein; Belongs to the bZIP family. | Mitogen-activated protein kinase kinase 4. | 0.769 |
| JUN | MAP2K7 | ENSOCUP00000040325 | ENSOCUP00000017722 | BZIP domain-containing protein; Belongs to the bZIP family. | Mitogen-activated protein kinase kinase 7. | 0.804 |
| JUN | MAP3K1 | ENSOCUP00000040325 | ENSOCUP00000035822 | BZIP domain-containing protein; Belongs to the bZIP family. | Mitogen-activated protein kinase kinase kinase 1. | 0.639 |
| JUN | MAPK10 | ENSOCUP00000040325 | ENSOCUP00000009184 | BZIP domain-containing protein; Belongs to the bZIP family. | Mitogen-activated protein kinase. | 0.995 |
| JUN | MAPK9 | ENSOCUP00000040325 | ENSOCUP00000031059 | BZIP domain-containing protein; Belongs to the bZIP family. | Mitogen-activated protein kinase. | 0.998 |
| JUN | NFATC3 | ENSOCUP00000040325 | ENSOCUP00000008660 | BZIP domain-containing protein; Belongs to the bZIP family. | Nuclear factor of activated T cells 3. | 0.627 |
| JUN | TP53 | ENSOCUP00000040325 | ENSOCUP00000000989 | BZIP domain-containing protein; Belongs to the bZIP family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] | 0.872 |
| MAP2K4 | JUN | ENSOCUP00000035427 | ENSOCUP00000040325 | Mitogen-activated protein kinase kinase 4. | BZIP domain-containing protein; Belongs to the bZIP family. | 0.769 |