NPY protein (Oryctolagus cuniculus) - STRING interaction network

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NPY

Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. (97 aa)

Predicted Functional Partners:

NPY2R

0.998

NPY5R

0.993

AGRP

0.977

POMC

0.972

NPY1R

0.964

NPY4R

0.948

SST

0.936

NPY6R

0.923

LEP

0.920

GHRL

0.919

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGRP	GHRL	ENSOCUP00000010187	ENSOCUP00000029787	Agouti related neuropeptide.	Uncharacterized protein.	0.926
AGRP	LEP	ENSOCUP00000010187	ENSOCUP00000008782	Agouti related neuropeptide.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.926
AGRP	NPY	ENSOCUP00000010187	ENSOCUP00000009261	Agouti related neuropeptide.	Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.	0.977
AGRP	NPY1R	ENSOCUP00000010187	ENSOCUP00000008576	Agouti related neuropeptide.	Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family.	0.550
AGRP	NPY2R	ENSOCUP00000010187	ENSOCUP00000019949	Agouti related neuropeptide.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.589
AGRP	NPY5R	ENSOCUP00000010187	ENSOCUP00000035450	Agouti related neuropeptide.	Neuropeptide Y receptor Y5.	0.633
AGRP	POMC	ENSOCUP00000010187	ENSOCUP00000037970	Agouti related neuropeptide.	NPP domain-containing protein.	0.983
AGRP	SST	ENSOCUP00000010187	ENSOCUP00000006540	Agouti related neuropeptide.	Somatostatin.	0.721
GHRL	AGRP	ENSOCUP00000029787	ENSOCUP00000010187	Uncharacterized protein.	Agouti related neuropeptide.	0.926
GHRL	LEP	ENSOCUP00000029787	ENSOCUP00000008782	Uncharacterized protein.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.982
GHRL	NPY	ENSOCUP00000029787	ENSOCUP00000009261	Uncharacterized protein.	Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.	0.919
GHRL	NPY1R	ENSOCUP00000029787	ENSOCUP00000008576	Uncharacterized protein.	Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family.	0.763
GHRL	NPY2R	ENSOCUP00000029787	ENSOCUP00000019949	Uncharacterized protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.733
GHRL	NPY4R	ENSOCUP00000029787	ENSOCUP00000012189	Uncharacterized protein.	Neuropeptide Y receptor Y4; Belongs to the G-protein coupled receptor 1 family.	0.714
GHRL	NPY6R	ENSOCUP00000029787	ENSOCUP00000023630	Uncharacterized protein.	Neuropeptide Y receptor type 6; Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.	0.714
GHRL	POMC	ENSOCUP00000029787	ENSOCUP00000037970	Uncharacterized protein.	NPP domain-containing protein.	0.887
GHRL	SST	ENSOCUP00000029787	ENSOCUP00000006540	Uncharacterized protein.	Somatostatin.	0.877
LEP	AGRP	ENSOCUP00000008782	ENSOCUP00000010187	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	Agouti related neuropeptide.	0.926
LEP	GHRL	ENSOCUP00000008782	ENSOCUP00000029787	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	Uncharacterized protein.	0.982
LEP	NPY	ENSOCUP00000008782	ENSOCUP00000009261	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.	0.920

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