Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGRP | LEP | ENSOCUP00000010187 | ENSOCUP00000008782 | Agouti related neuropeptide. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.942 |
| AGRP | NPY | ENSOCUP00000010187 | ENSOCUP00000009261 | Agouti related neuropeptide. | Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | 0.985 |
| AGRP | NPY1R | ENSOCUP00000010187 | ENSOCUP00000008576 | Agouti related neuropeptide. | Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. | 0.519 |
| AGRP | NPY2R | ENSOCUP00000010187 | ENSOCUP00000019949 | Agouti related neuropeptide. | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | 0.470 |
| AGRP | NPY5R | ENSOCUP00000010187 | ENSOCUP00000035450 | Agouti related neuropeptide. | Neuropeptide Y receptor Y5. | 0.533 |
| AGRP | POMC | ENSOCUP00000010187 | ENSOCUP00000037970 | Agouti related neuropeptide. | NPP domain-containing protein. | 0.986 |
| AGRP | PPY | ENSOCUP00000010187 | ENSOCUP00000025326 | Agouti related neuropeptide. | Pancreatic hormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family. | 0.507 |
| AGRP | PYY | ENSOCUP00000010187 | ENSOCUP00000011243 | Agouti related neuropeptide. | Peptide YY(3-36); This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. | 0.777 |
| AGRP | SST | ENSOCUP00000010187 | ENSOCUP00000006540 | Agouti related neuropeptide. | Somatostatin. | 0.553 |
| LEP | AGRP | ENSOCUP00000008782 | ENSOCUP00000010187 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | Agouti related neuropeptide. | 0.942 |
| LEP | NPY | ENSOCUP00000008782 | ENSOCUP00000009261 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | 0.945 |
| LEP | POMC | ENSOCUP00000008782 | ENSOCUP00000037970 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | NPP domain-containing protein. | 0.937 |
| LEP | PPY | ENSOCUP00000008782 | ENSOCUP00000025326 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | Pancreatic hormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family. | 0.511 |
| LEP | PYY | ENSOCUP00000008782 | ENSOCUP00000011243 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | Peptide YY(3-36); This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. | 0.823 |
| LEP | SST | ENSOCUP00000008782 | ENSOCUP00000006540 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | Somatostatin. | 0.749 |
| NPY | AGRP | ENSOCUP00000009261 | ENSOCUP00000010187 | Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Agouti related neuropeptide. | 0.985 |
| NPY | LEP | ENSOCUP00000009261 | ENSOCUP00000008782 | Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] | 0.945 |
| NPY | NPY1R | ENSOCUP00000009261 | ENSOCUP00000008576 | Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Neuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. | 0.995 |
| NPY | NPY2R | ENSOCUP00000009261 | ENSOCUP00000019949 | Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. | 0.999 |
| NPY | NPY4R | ENSOCUP00000009261 | ENSOCUP00000012189 | Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | Neuropeptide Y receptor Y4; Belongs to the G-protein coupled receptor 1 family. | 0.978 |
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