Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LRRC8BLeucine rich repeat containing 8 VRAC subunit B. (859 aa)    
Predicted Functional Partners:
LRRC8A
Leucine rich repeat containing 8 VRAC subunit A.
    
 0.985
LRRC8D
Leucine rich repeat containing 8 VRAC subunit D.
    
  0.892
LRRC8C
Leucine rich repeat containing 8 VRAC subunit C.
    
 0.862
LRRC8E
Leucine rich repeat containing 8 VRAC subunit E.
    
 0.757
LRRIQ4
Leucine rich repeats and IQ motif containing 4.
  
 
 
0.664
NPEPPS
Aminopeptidase.
    
  0.650
BEST1
Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.
      
 0.587
TRMT13
tRNA methyltransferase 13 homolog.
      
 0.587
BEST2
Bestrophin; Forms calcium-sensitive chloride channels. Permeable to bicarbonate; Belongs to the bestrophin family.
      
 0.581
TPGS2
Tubulin polyglutamylase complex subunit 2.
    
 0.579
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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