STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBX4T-box transcription factor 4. (550 aa)    
Predicted Functional Partners:
NKX2-5
NK2 homeobox 5.
   
 
 0.764
HOXC10
Homeobox C10.
    
 
 0.700
TBL1XR1
Transducin beta like 1 X-linked receptor 1.
   
 
 0.694
FGFBP1
Fibroblast growth factor binding protein 1.
      
 0.643
PROM1
Prominin 1.
   
  
 0.638
PITX2
Homeobox protein.
   
 
 0.629
BCAS3
BCAS3 microtubule associated cell migration factor.
      
 0.582
FGF10
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
  
 0.575
BMP2
Bone morphogenetic protein 2; Induces cartilage and bone formation. Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3- EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4.
     
 0.553
MAGEB10
MAGE family member B10.
      
 0.543
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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