STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZC3H12AZinc finger CCCH-type containing 12A. (580 aa)    
Predicted Functional Partners:
TANK
TRAF family member associated NFKB activator.
   
 
 0.671
NFKBIZ
ANK_REP_REGION domain-containing protein.
   
 
 0.668
RC3H1
Ring finger and CCCH-type domains 1.
   
  
 0.617
TCIM
Transcriptional and immune response regulator.
      
 0.572
TTC14
Tetratricopeptide repeat domain 14.
      
 0.557
RND1
Rho family GTPase 1.
   
  
 0.509
IL6
Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...]
   
 
 0.503
LOC100346467
GB1/RHD3-type G domain-containing protein.
      
 0.495
TM2D3
TM2 domain containing 3.
      
 0.489
TNFAIP3
TNF alpha induced protein 3.
   
 
 0.455
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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