ABCB5 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

ABCB5

ATP binding cassette subfamily B member 5. (1258 aa)

Predicted Functional Partners:

SUOX

0.866

KRT12

0.688

HIP1

0.605

ACACB

0.569

ACACA

0.569

NR1H4

0.540

TJP2

0.533

MARCHF6

0.518

ACLY

0.515

CYP7A1

0.510

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCB5	ACACA	ENSOCUP00000009345	ENSOCUP00000012460	ATP binding cassette subfamily B member 5.	Acetyl-CoA carboxylase alpha.	0.569
ABCB5	ACACB	ENSOCUP00000009345	ENSOCUP00000006434	ATP binding cassette subfamily B member 5.	Acetyl-CoA carboxylase beta.	0.569
ABCB5	ACLY	ENSOCUP00000009345	ENSOCUP00000029663	ATP binding cassette subfamily B member 5.	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	0.515
ABCB5	CYP7A1	ENSOCUP00000009345	ENSOCUP00000010572	ATP binding cassette subfamily B member 5.	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...]	0.510
ABCB5	HIP1	ENSOCUP00000009345	ENSOCUP00000029732	ATP binding cassette subfamily B member 5.	Huntingtin interacting protein 1.	0.605
ABCB5	KRT12	ENSOCUP00000009345	ENSOCUP00000015186	ATP binding cassette subfamily B member 5.	Keratin, type I cytoskeletal 12; May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity (By similarity); Belongs to the intermediate filament family.	0.688
ABCB5	MARCHF6	ENSOCUP00000009345	ENSOCUP00000004979	ATP binding cassette subfamily B member 5.	Membrane associated ring-CH-type finger 6.	0.518
ABCB5	NR1H4	ENSOCUP00000009345	ENSOCUP00000006201	ATP binding cassette subfamily B member 5.	Uncharacterized protein.	0.540
ABCB5	SUOX	ENSOCUP00000009345	ENSOCUP00000000860	ATP binding cassette subfamily B member 5.	Sulfite oxidase.	0.866
ABCB5	TJP2	ENSOCUP00000009345	ENSOCUP00000034418	ATP binding cassette subfamily B member 5.	Uncharacterized protein; Belongs to the MAGUK family.	0.533
ACACA	ABCB5	ENSOCUP00000012460	ENSOCUP00000009345	Acetyl-CoA carboxylase alpha.	ATP binding cassette subfamily B member 5.	0.569
ACACA	ACACB	ENSOCUP00000012460	ENSOCUP00000006434	Acetyl-CoA carboxylase alpha.	Acetyl-CoA carboxylase beta.	0.991
ACACA	ACLY	ENSOCUP00000012460	ENSOCUP00000029663	Acetyl-CoA carboxylase alpha.	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	0.982
ACACA	CYP7A1	ENSOCUP00000012460	ENSOCUP00000010572	Acetyl-CoA carboxylase alpha.	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...]	0.549
ACACB	ABCB5	ENSOCUP00000006434	ENSOCUP00000009345	Acetyl-CoA carboxylase beta.	ATP binding cassette subfamily B member 5.	0.569
ACACB	ACACA	ENSOCUP00000006434	ENSOCUP00000012460	Acetyl-CoA carboxylase beta.	Acetyl-CoA carboxylase alpha.	0.991
ACACB	ACLY	ENSOCUP00000006434	ENSOCUP00000029663	Acetyl-CoA carboxylase beta.	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	0.968
ACACB	CYP7A1	ENSOCUP00000006434	ENSOCUP00000010572	Acetyl-CoA carboxylase beta.	Cytochrome P450 7A1; A cytochrome P450 monooxygenase involved in the metabolism of endogenous cholesterol and its oxygenated derivatives (oxysterols) (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase) (By similarity). Functions as a critical regulatory enzyme of bile acid biosynthesis and cholesterol homeostasis (Probable). Catalyzes the hydroxylation of carbon hydrogen bond at 7-alpha [...]	0.403
ACLY	ABCB5	ENSOCUP00000029663	ENSOCUP00000009345	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	ATP binding cassette subfamily B member 5.	0.515
ACLY	ACACA	ENSOCUP00000029663	ENSOCUP00000012460	ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.	Acetyl-CoA carboxylase alpha.	0.982