Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
G1T067_RABITFam20C domain-containing protein. (543 aa)    
Predicted Functional Partners:
FAM20A
FAM20A golgi associated secretory pathway pseudokinase.
    
 0.983
FGF23
Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family.
    
 0.885
SPP1
Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction; Belongs to the osteopontin family.
    
 0.870
PCSK9
Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.
    
 0.848
FGA
Fibrinogen alpha chain.
    
  0.828
CKAP4
Cytoskeleton associated protein 4.
    
 0.824
NUCB1
Nucleobindin 1.
    
 0.824
BMP15
TGF_BETA_2 domain-containing protein.
    
 0.800
HSP90B1
Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.
    
 0.797
AHSG
Alpha-2-HS-glycoprotein; A cell adhesion protein that binds immature cells of the granulocyte lineage; Belongs to the fetuin family.
    
  0.797
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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