ACKR3 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

ACKR3

Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (336 aa)

Predicted Functional Partners:

CXCR4

0.990

G1U9D6_RABIT

0.969

CXCL11

0.906

ARRB1

0.755

ARR3

0.632

CXCL10

0.627

CXCL9

0.623

CCL21

0.609

CCL19

0.609

CCL25

0.600

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACKR3	ARR3	ENSOCUP00000009382	ENSOCUP00000014674	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Arrestin 3.	0.632
ACKR3	ARRB1	ENSOCUP00000009382	ENSOCUP00000019641	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	0.755
ACKR3	CCL19	ENSOCUP00000009382	ENSOCUP00000038810	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine.	0.609
ACKR3	CCL21	ENSOCUP00000009382	ENSOCUP00000020728	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-C motif chemokine ligand 21.	0.609
ACKR3	CCL25	ENSOCUP00000009382	ENSOCUP00000041029	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	SCY domain-containing protein.	0.600
ACKR3	CXCL10	ENSOCUP00000009382	ENSOCUP00000013990	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.627
ACKR3	CXCL11	ENSOCUP00000009382	ENSOCUP00000049211	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine ligand 11.	0.906
ACKR3	CXCL9	ENSOCUP00000009382	ENSOCUP00000026932	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine.	0.623
ACKR3	CXCR4	ENSOCUP00000009382	ENSOCUP00000001655	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.990
ACKR3	G1U9D6_RABIT	ENSOCUP00000009382	ENSOCUP00000026057	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.969
ARR3	ACKR3	ENSOCUP00000014674	ENSOCUP00000009382	Arrestin 3.	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.632
ARRB1	ACKR3	ENSOCUP00000019641	ENSOCUP00000009382	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.755
ARRB1	CXCR4	ENSOCUP00000019641	ENSOCUP00000001655	Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...]	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.773
CCL19	ACKR3	ENSOCUP00000038810	ENSOCUP00000009382	C-C motif chemokine.	Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.609
CCL19	CCL21	ENSOCUP00000038810	ENSOCUP00000020728	C-C motif chemokine.	C-C motif chemokine ligand 21.	0.946
CCL19	CCL25	ENSOCUP00000038810	ENSOCUP00000041029	C-C motif chemokine.	SCY domain-containing protein.	0.891
CCL19	CXCL10	ENSOCUP00000038810	ENSOCUP00000013990	C-C motif chemokine.	C-X-C motif chemokine.	0.850
CCL19	CXCL11	ENSOCUP00000038810	ENSOCUP00000049211	C-C motif chemokine.	C-X-C motif chemokine ligand 11.	0.875
CCL19	CXCL9	ENSOCUP00000038810	ENSOCUP00000026932	C-C motif chemokine.	C-X-C motif chemokine.	0.856
CCL19	CXCR4	ENSOCUP00000038810	ENSOCUP00000001655	C-C motif chemokine.	C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family.	0.967