IRS4 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

IRS4

Insulin receptor substrate 4. (1176 aa)

Predicted Functional Partners:

GRB2

0.993

INSR

0.981

PIK3R1

0.979

LOC100345250

0.975

INS

0.975

IRS1

0.959

JAK2

0.959

PIK3CA

0.958

PIK3CB

0.957

PIK3CG

0.956

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GRB2	INS	ENSOCUP00000042433	ENSOCUP00000020463	Growth factor receptor bound protein 2.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.797
GRB2	INSR	ENSOCUP00000042433	ENSOCUP00000042281	Growth factor receptor bound protein 2.	Tyrosine-protein kinase receptor.	0.978
GRB2	IRS1	ENSOCUP00000042433	ENSOCUP00000006209	Growth factor receptor bound protein 2.	Insulin receptor substrate 1.	0.999
GRB2	IRS4	ENSOCUP00000042433	ENSOCUP00000009383	Growth factor receptor bound protein 2.	Insulin receptor substrate 4.	0.993
GRB2	JAK2	ENSOCUP00000042433	ENSOCUP00000014491	Growth factor receptor bound protein 2.	Tyrosine-protein kinase.	0.887
GRB2	LOC100345250	ENSOCUP00000042433	ENSOCUP00000012307	Growth factor receptor bound protein 2.	Uncharacterized protein.	0.846
GRB2	PIK3CA	ENSOCUP00000042433	ENSOCUP00000026298	Growth factor receptor bound protein 2.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.744
GRB2	PIK3CB	ENSOCUP00000042433	ENSOCUP00000004241	Growth factor receptor bound protein 2.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family.	0.635
GRB2	PIK3CG	ENSOCUP00000042433	ENSOCUP00000010960	Growth factor receptor bound protein 2.	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family.	0.621
GRB2	PIK3R1	ENSOCUP00000042433	ENSOCUP00000004433	Growth factor receptor bound protein 2.	Phosphoinositide-3-kinase regulatory subunit 1.	0.981
INS	GRB2	ENSOCUP00000020463	ENSOCUP00000042433	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Growth factor receptor bound protein 2.	0.797
INS	INSR	ENSOCUP00000020463	ENSOCUP00000042281	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.999
INS	IRS1	ENSOCUP00000020463	ENSOCUP00000006209	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin receptor substrate 1.	0.996
INS	IRS4	ENSOCUP00000020463	ENSOCUP00000009383	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin receptor substrate 4.	0.975
INS	JAK2	ENSOCUP00000020463	ENSOCUP00000014491	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase.	0.731
INS	LOC100345250	ENSOCUP00000020463	ENSOCUP00000012307	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.439
INS	PIK3CA	ENSOCUP00000020463	ENSOCUP00000026298	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.578
INS	PIK3R1	ENSOCUP00000020463	ENSOCUP00000004433	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Phosphoinositide-3-kinase regulatory subunit 1.	0.536
INSR	GRB2	ENSOCUP00000042281	ENSOCUP00000042433	Tyrosine-protein kinase receptor.	Growth factor receptor bound protein 2.	0.978
INSR	INS	ENSOCUP00000042281	ENSOCUP00000020463	Tyrosine-protein kinase receptor.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.999