node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADORA1 | ADORA2A | ENSOCUP00000009475 | ENSOCUP00000007521 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | 0.723 |
ADORA1 | ADORA3 | ENSOCUP00000009475 | ENSOCUP00000017694 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. | 0.958 |
ADORA1 | EDN1 | ENSOCUP00000009475 | ENSOCUP00000011526 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | 0.735 |
ADORA1 | GHRL | ENSOCUP00000009475 | ENSOCUP00000029787 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | Uncharacterized protein. | 0.727 |
ADORA1 | GNAI1 | ENSOCUP00000009475 | ENSOCUP00000000882 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | G protein subunit alpha i1. | 0.933 |
ADORA1 | GNAI2 | ENSOCUP00000009475 | ENSOCUP00000019624 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | G protein subunit alpha i2. | 0.975 |
ADORA1 | GNAI3 | ENSOCUP00000009475 | ENSOCUP00000004821 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | G protein subunit alpha i3. | 0.933 |
ADORA1 | KNG1 | ENSOCUP00000009475 | ENSOCUP00000033073 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | Kininogen 1. | 0.912 |
ADORA1 | OXT | ENSOCUP00000009475 | ENSOCUP00000045888 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | Oxytocin; Belongs to the vasopressin/oxytocin family. | 0.717 |
ADORA1 | SST | ENSOCUP00000009475 | ENSOCUP00000006540 | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | Somatostatin. | 0.722 |
ADORA2A | ADORA1 | ENSOCUP00000007521 | ENSOCUP00000009475 | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | 0.723 |
ADORA2A | ADORA3 | ENSOCUP00000007521 | ENSOCUP00000017694 | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. | 0.478 |
ADORA3 | ADORA1 | ENSOCUP00000017694 | ENSOCUP00000009475 | Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | 0.958 |
ADORA3 | ADORA2A | ENSOCUP00000017694 | ENSOCUP00000007521 | Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | 0.478 |
ADORA3 | GNAI1 | ENSOCUP00000017694 | ENSOCUP00000000882 | Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. | G protein subunit alpha i1. | 0.933 |
ADORA3 | GNAI2 | ENSOCUP00000017694 | ENSOCUP00000019624 | Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. | G protein subunit alpha i2. | 0.933 |
ADORA3 | GNAI3 | ENSOCUP00000017694 | ENSOCUP00000004821 | Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. | G protein subunit alpha i3. | 0.933 |
ADORA3 | KNG1 | ENSOCUP00000017694 | ENSOCUP00000033073 | Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. | Kininogen 1. | 0.908 |
EDN1 | ADORA1 | ENSOCUP00000011526 | ENSOCUP00000009475 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. | 0.735 |
EDN1 | GHRL | ENSOCUP00000011526 | ENSOCUP00000029787 | Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. | Uncharacterized protein. | 0.467 |