STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRP2Uncharacterized protein. (2726 aa)    
Predicted Functional Partners:
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
     
 0.976
PTCH1
Patched 1.
   
 
 0.929
TG
COesterase domain-containing protein.
     
 0.927
ANKRA2
Ankyrin repeat family A member 2.
    
 0.921
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
     
 0.919
PTCH2
Patched 2.
   
 
 0.917
CDON
Cell adhesion associated, oncogene regulated.
     
 0.916
DHH
Desert hedgehog signaling molecule.
     
 0.910
BOC
BOC cell adhesion associated, oncogene regulated.
   
 
 0.904
CUBN
Cubilin.
   
 0.898
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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