STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESM1Endothelial cell specific molecule 1. (231 aa)    
Predicted Functional Partners:
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
     
 0.645
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
      
 0.624
PDGFB
Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.
      
 0.596
EMCN
Endomucin.
   
  
 0.577
APLN
Apelin.
   
  
 0.571
EFNB2
Ephrin B2; Belongs to the ephrin family.
      
 0.547
FLYWCH2
FLYWCH_N domain-containing protein.
      
 0.546
ID3
Inhibitor of DNA binding 3, HLH protein.
      
 0.545
ANGPT2
Angiopoietin 2.
   
 
 0.507
UNC5B
Unc-5 netrin receptor B.
   
  
 0.496
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.