MYL3 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MYBPC3	MYH1	ENSOCUP00000001825	ENSOCUP00000017571	Myosin binding protein C, cardiac.	Myosin-4; Muscle contraction.	0.730
MYBPC3	MYH4	ENSOCUP00000001825	ENSOCUP00000002961	Myosin binding protein C, cardiac.	Myosin-4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.730
MYBPC3	MYH7	ENSOCUP00000001825	ENSOCUP00000021291	Myosin binding protein C, cardiac.	Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.950
MYBPC3	MYH8	ENSOCUP00000001825	ENSOCUP00000008830	Myosin binding protein C, cardiac.	Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.762
MYBPC3	MYL1	ENSOCUP00000001825	ENSOCUP00000038248	Myosin binding protein C, cardiac.	Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.	0.668
MYBPC3	MYL2	ENSOCUP00000001825	ENSOCUP00000028408	Myosin binding protein C, cardiac.	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...]	0.955
MYBPC3	MYL3	ENSOCUP00000001825	ENSOCUP00000029317	Myosin binding protein C, cardiac.	Myosin light chain 3.	0.971
MYBPC3	MYL4	ENSOCUP00000001825	ENSOCUP00000037806	Myosin binding protein C, cardiac.	Myosin light chain 4.	0.849
MYBPC3	MYLK2	ENSOCUP00000001825	ENSOCUP00000040286	Myosin binding protein C, cardiac.	Myosin light chain kinase 2, skeletal/cardiac muscle; Implicated in the level of global muscle contraction and cardiac function (By similarity). Phosphorylates a specific serine in the N-terminus of a myosin light chain.	0.556
MYBPC3	TNNI1	ENSOCUP00000001825	ENSOCUP00000008977	Myosin binding protein C, cardiac.	Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.658
MYH1	MYBPC3	ENSOCUP00000017571	ENSOCUP00000001825	Myosin-4; Muscle contraction.	Myosin binding protein C, cardiac.	0.730
MYH1	MYH4	ENSOCUP00000017571	ENSOCUP00000002961	Myosin-4; Muscle contraction.	Myosin-4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.632
MYH1	MYH7	ENSOCUP00000017571	ENSOCUP00000021291	Myosin-4; Muscle contraction.	Myosin-7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.557
MYH1	MYH8	ENSOCUP00000017571	ENSOCUP00000008830	Myosin-4; Muscle contraction.	Myosin heavy chain 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.554
MYH1	MYL1	ENSOCUP00000017571	ENSOCUP00000038248	Myosin-4; Muscle contraction.	Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function.	0.959
MYH1	MYL2	ENSOCUP00000017571	ENSOCUP00000028408	Myosin-4; Muscle contraction.	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...]	0.897
MYH1	MYL3	ENSOCUP00000017571	ENSOCUP00000029317	Myosin-4; Muscle contraction.	Myosin light chain 3.	0.960
MYH1	MYL4	ENSOCUP00000017571	ENSOCUP00000037806	Myosin-4; Muscle contraction.	Myosin light chain 4.	0.919
MYH1	MYLK2	ENSOCUP00000017571	ENSOCUP00000040286	Myosin-4; Muscle contraction.	Myosin light chain kinase 2, skeletal/cardiac muscle; Implicated in the level of global muscle contraction and cardiac function (By similarity). Phosphorylates a specific serine in the N-terminus of a myosin light chain.	0.501
MYH1	TNNI1	ENSOCUP00000017571	ENSOCUP00000008977	Myosin-4; Muscle contraction.	Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.867