node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASB5 | CALHM2 | ENSOCUP00000010841 | ENSOCUP00000005477 | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis. | Calcium homeostasis modulator family member 2. | 0.599 |
ASB5 | CUL5 | ENSOCUP00000010841 | ENSOCUP00000009389 | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis. | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] | 0.624 |
ASB5 | ELOB | ENSOCUP00000010841 | ENSOCUP00000008716 | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis. | Elongin B. | 0.606 |
ASB5 | ENSOCUP00000030350 | ENSOCUP00000010841 | ENSOCUP00000030350 | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis. | Skp1_POZ domain-containing protein. | 0.553 |
ASB5 | G1SG29_RABIT | ENSOCUP00000010841 | ENSOCUP00000001516 | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis. | Skp1_POZ domain-containing protein. | 0.553 |
ASB5 | G1U1I7_RABIT | ENSOCUP00000010841 | ENSOCUP00000023222 | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis. | Uncharacterized protein. | 0.606 |
ASB5 | NEURL2 | ENSOCUP00000010841 | ENSOCUP00000016020 | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis. | Neuralized E3 ubiquitin protein ligase 2. | 0.650 |
ASB5 | PERM1 | ENSOCUP00000010841 | ENSOCUP00000020860 | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis. | PPARGC1 and ESRR induced regulator, muscle 1. | 0.604 |
ASB5 | PHYHIP | ENSOCUP00000010841 | ENSOCUP00000008531 | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis. | Phytanoyl-CoA 2-hydroxylase interacting protein. | 0.553 |
ASB5 | ZFAND3 | ENSOCUP00000010841 | ENSOCUP00000014804 | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis. | Zinc finger AN1-type containing 3. | 0.568 |
CALHM2 | ASB5 | ENSOCUP00000005477 | ENSOCUP00000010841 | Calcium homeostasis modulator family member 2. | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis. | 0.599 |
CALHM2 | PERM1 | ENSOCUP00000005477 | ENSOCUP00000020860 | Calcium homeostasis modulator family member 2. | PPARGC1 and ESRR induced regulator, muscle 1. | 0.596 |
CALHM2 | PHYHIP | ENSOCUP00000005477 | ENSOCUP00000008531 | Calcium homeostasis modulator family member 2. | Phytanoyl-CoA 2-hydroxylase interacting protein. | 0.599 |
CALHM2 | ZFAND3 | ENSOCUP00000005477 | ENSOCUP00000014804 | Calcium homeostasis modulator family member 2. | Zinc finger AN1-type containing 3. | 0.597 |
CUL5 | ASB5 | ENSOCUP00000009389 | ENSOCUP00000010841 | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). May play a role in the initiation of arteriogenesis. | 0.624 |
CUL5 | ELOB | ENSOCUP00000009389 | ENSOCUP00000008716 | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] | Elongin B. | 0.999 |
CUL5 | ENSOCUP00000030350 | ENSOCUP00000009389 | ENSOCUP00000030350 | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] | Skp1_POZ domain-containing protein. | 0.859 |
CUL5 | G1SG29_RABIT | ENSOCUP00000009389 | ENSOCUP00000001516 | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] | Skp1_POZ domain-containing protein. | 0.884 |
CUL5 | G1U1I7_RABIT | ENSOCUP00000009389 | ENSOCUP00000023222 | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] | Uncharacterized protein. | 0.930 |
CUL5 | NEURL2 | ENSOCUP00000009389 | ENSOCUP00000016020 | Cullin-5; Core component of multiple SCF-like ECS (Elongin BC-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimula [...] | Neuralized E3 ubiquitin protein ligase 2. | 0.656 |