TBX5 protein (Oryctolagus cuniculus) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

TBX5

T-box transcription factor 5. (518 aa)

Predicted Functional Partners:

NKX2-5

0.999

YAP1

0.970

GATA4

0.965

HAND2

0.889

MEF2C

0.876

MYOCD

0.817

TNNT2

0.790

ISL1

0.785

SMARCD3

0.768

NPPA

0.758

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GATA4	HAND2	ENSOCUP00000001897	ENSOCUP00000013968	GATA binding protein 4.	BHLH domain-containing protein.	0.943
GATA4	ISL1	ENSOCUP00000001897	ENSOCUP00000020036	GATA binding protein 4.	ISL LIM homeobox 1.	0.782
GATA4	MEF2C	ENSOCUP00000001897	ENSOCUP00000047636	GATA binding protein 4.	Myocyte enhancer factor 2C.	0.935
GATA4	MYOCD	ENSOCUP00000001897	ENSOCUP00000023668	GATA binding protein 4.	Myocardin.	0.709
GATA4	NKX2-5	ENSOCUP00000001897	ENSOCUP00000000038	GATA binding protein 4.	NK2 homeobox 5.	0.999
GATA4	NPPA	ENSOCUP00000001897	ENSOCUP00000006321	GATA binding protein 4.	Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity); Belongs to the natriuretic peptide family.	0.833
GATA4	SMARCD3	ENSOCUP00000001897	ENSOCUP00000048837	GATA binding protein 4.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3.	0.683
GATA4	TBX5	ENSOCUP00000001897	ENSOCUP00000010944	GATA binding protein 4.	T-box transcription factor 5.	0.965
GATA4	TNNT2	ENSOCUP00000001897	ENSOCUP00000018870	GATA binding protein 4.	Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.823
HAND2	GATA4	ENSOCUP00000013968	ENSOCUP00000001897	BHLH domain-containing protein.	GATA binding protein 4.	0.943
HAND2	ISL1	ENSOCUP00000013968	ENSOCUP00000020036	BHLH domain-containing protein.	ISL LIM homeobox 1.	0.816
HAND2	MEF2C	ENSOCUP00000013968	ENSOCUP00000047636	BHLH domain-containing protein.	Myocyte enhancer factor 2C.	0.804
HAND2	MYOCD	ENSOCUP00000013968	ENSOCUP00000023668	BHLH domain-containing protein.	Myocardin.	0.749
HAND2	NKX2-5	ENSOCUP00000013968	ENSOCUP00000000038	BHLH domain-containing protein.	NK2 homeobox 5.	0.942
HAND2	NPPA	ENSOCUP00000013968	ENSOCUP00000006321	BHLH domain-containing protein.	Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3 (By similarity); Belongs to the natriuretic peptide family.	0.639
HAND2	TBX5	ENSOCUP00000013968	ENSOCUP00000010944	BHLH domain-containing protein.	T-box transcription factor 5.	0.889
HAND2	TNNT2	ENSOCUP00000013968	ENSOCUP00000018870	BHLH domain-containing protein.	Troponin T, cardiac muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.	0.628
ISL1	GATA4	ENSOCUP00000020036	ENSOCUP00000001897	ISL LIM homeobox 1.	GATA binding protein 4.	0.782
ISL1	HAND2	ENSOCUP00000020036	ENSOCUP00000013968	ISL LIM homeobox 1.	BHLH domain-containing protein.	0.816
ISL1	MEF2C	ENSOCUP00000020036	ENSOCUP00000047636	ISL LIM homeobox 1.	Myocyte enhancer factor 2C.	0.767