STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM181Transmembrane protein 181. (535 aa)    
Predicted Functional Partners:
SGMS1
Sphingomyelin synthase 1.
   
  
 0.749
ALDH18A1
Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
   
  
 0.562
PODXL
Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...]
   
  
 0.507
TULP4
TUB like protein 4; Belongs to the TUB family.
   
  
 0.496
G1TGR2_RABIT
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
      
 0.493
UGT3A2
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
  
 0.491
AGT
Angiotensinogen; Belongs to the serpin family.
   
 0.454
EFL1
Elongation factor like GTPase 1.
   
 
 0.427
LOC100338508
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
      
 0.426
LOC100357038
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
      
 0.426
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.