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RHO protein (Oryctolagus cuniculus) - STRING interaction network
"RHO" - Rhodopsin in Oryctolagus cuniculus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
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RHORhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity) (348 aa)    
Predicted Functional Partners:
GRK1
G protein-coupled receptor kinase 1 (233 aa)
     
  0.997
SAG
S-antigen; retina and pineal gland (arrestin) (400 aa)
     
 
  0.990
GNAT2
Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 (354 aa)
     
  0.986
GRK7
G protein-coupled receptor kinase 7; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily (527 aa)
     
  0.981
SRP54
Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein); Belongs to the GTP-binding SRP family. SRP54 subfamily (503 aa)
       
 
  0.979
SRP14
Signal recognition particle 14kDa (homologous Alu RNA binding protein) (110 aa)
       
 
  0.979
SRP9
Signal recognition particle 9 kDa protein; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding (86 aa)
       
      0.979
GNB1
G protein subunit beta 1; Guanine nucleotide binding protein (G protein), beta polypeptide 1 (340 aa)
       
  0.976
GNGT1
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (74 aa)
     
  0.918
SRP19
Uncharacterized protein (145 aa)
       
      0.910
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, Oryctolagus cuniculus, domestic rabbit, rabbit, rabbits
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