MELTF protein (Oryctolagus cuniculus) - STRING interaction network

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MELTF

Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family. (698 aa)

Predicted Functional Partners:

TFRC

0.914

HPGDS

0.759

EPO

0.664

ALDH16A1

0.560

HEBP1

0.553

SRPRB

0.544

MIS12

0.544

LRP2

0.508

TEX15

0.494

PIEZO2

0.493

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH16A1	MELTF	ENSOCUP00000018035	ENSOCUP00000011582	Aldehyde dehydrogenase 16 family member A1.	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	0.560
EPO	MELTF	ENSOCUP00000004681	ENSOCUP00000011582	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	0.664
EPO	TFRC	ENSOCUP00000004681	ENSOCUP00000014641	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	Transferrin receptor.	0.681
HEBP1	MELTF	ENSOCUP00000013181	ENSOCUP00000011582	Heme binding protein 1.	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	0.553
HPGDS	MELTF	ENSOCUP00000014861	ENSOCUP00000011582	Hematopoietic prostaglandin D synthase.	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	0.759
LRP2	MELTF	ENSOCUP00000009497	ENSOCUP00000011582	Uncharacterized protein.	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	0.508
LRP2	TFRC	ENSOCUP00000009497	ENSOCUP00000014641	Uncharacterized protein.	Transferrin receptor.	0.511
MELTF	ALDH16A1	ENSOCUP00000011582	ENSOCUP00000018035	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	Aldehyde dehydrogenase 16 family member A1.	0.560
MELTF	EPO	ENSOCUP00000011582	ENSOCUP00000004681	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family.	0.664
MELTF	HEBP1	ENSOCUP00000011582	ENSOCUP00000013181	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	Heme binding protein 1.	0.553
MELTF	HPGDS	ENSOCUP00000011582	ENSOCUP00000014861	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	Hematopoietic prostaglandin D synthase.	0.759
MELTF	LRP2	ENSOCUP00000011582	ENSOCUP00000009497	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	Uncharacterized protein.	0.508
MELTF	MIS12	ENSOCUP00000011582	ENSOCUP00000016093	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	MIS12 kinetochore complex component.	0.544
MELTF	PIEZO2	ENSOCUP00000011582	ENSOCUP00000040500	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	Piezo-type mechanosensitive ion channel component.	0.493
MELTF	SRPRB	ENSOCUP00000011582	ENSOCUP00000006592	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	SRP receptor subunit beta.	0.544
MELTF	TEX15	ENSOCUP00000011582	ENSOCUP00000037703	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	Testis expressed 15, meiosis and synapsis associated.	0.494
MELTF	TFRC	ENSOCUP00000011582	ENSOCUP00000014641	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	Transferrin receptor.	0.914
MIS12	MELTF	ENSOCUP00000016093	ENSOCUP00000011582	MIS12 kinetochore complex component.	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	0.544
PIEZO2	MELTF	ENSOCUP00000040500	ENSOCUP00000011582	Piezo-type mechanosensitive ion channel component.	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	0.493
SRPRB	MELTF	ENSOCUP00000006592	ENSOCUP00000011582	SRP receptor subunit beta.	Melanotransferrin; Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc (By similarity); Belongs to the transferrin family.	0.544

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