UCN3 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

UCN3

Urocortin 3. (167 aa)

Predicted Functional Partners:

CRHR2

0.991

UCN

0.981

CRHR1

0.975

CRH

0.964

SST

0.673

GCG

0.667

SLC30A8

0.650

GLP1R

0.612

PPY

0.610

CRHBP

0.594

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRH	CRHBP	ENSOCUP00000047659	ENSOCUP00000031093	CRF domain-containing protein.	Corticotropin releasing hormone binding protein.	0.965
CRH	CRHR1	ENSOCUP00000047659	ENSOCUP00000034660	CRF domain-containing protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.999
CRH	CRHR2	ENSOCUP00000047659	ENSOCUP00000039690	CRF domain-containing protein.	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family.	0.999
CRH	GCG	ENSOCUP00000047659	ENSOCUP00000019727	CRF domain-containing protein.	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	0.437
CRH	GLP1R	ENSOCUP00000047659	ENSOCUP00000041020	CRF domain-containing protein.	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	0.734
CRH	SST	ENSOCUP00000047659	ENSOCUP00000006540	CRF domain-containing protein.	Somatostatin.	0.779
CRH	UCN	ENSOCUP00000047659	ENSOCUP00000014644	CRF domain-containing protein.	Urocortin.	0.976
CRH	UCN3	ENSOCUP00000047659	ENSOCUP00000011846	CRF domain-containing protein.	Urocortin 3.	0.964
CRHBP	CRH	ENSOCUP00000031093	ENSOCUP00000047659	Corticotropin releasing hormone binding protein.	CRF domain-containing protein.	0.965
CRHBP	CRHR1	ENSOCUP00000031093	ENSOCUP00000034660	Corticotropin releasing hormone binding protein.	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	0.745
CRHBP	CRHR2	ENSOCUP00000031093	ENSOCUP00000039690	Corticotropin releasing hormone binding protein.	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family.	0.689
CRHBP	SST	ENSOCUP00000031093	ENSOCUP00000006540	Corticotropin releasing hormone binding protein.	Somatostatin.	0.467
CRHBP	UCN	ENSOCUP00000031093	ENSOCUP00000014644	Corticotropin releasing hormone binding protein.	Urocortin.	0.835
CRHBP	UCN3	ENSOCUP00000031093	ENSOCUP00000011846	Corticotropin releasing hormone binding protein.	Urocortin 3.	0.594
CRHR1	CRH	ENSOCUP00000034660	ENSOCUP00000047659	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	CRF domain-containing protein.	0.999
CRHR1	CRHBP	ENSOCUP00000034660	ENSOCUP00000031093	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Corticotropin releasing hormone binding protein.	0.745
CRHR1	CRHR2	ENSOCUP00000034660	ENSOCUP00000039690	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family.	0.915
CRHR1	GCG	ENSOCUP00000034660	ENSOCUP00000019727	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	0.430
CRHR1	SST	ENSOCUP00000034660	ENSOCUP00000006540	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Somatostatin.	0.406
CRHR1	UCN	ENSOCUP00000034660	ENSOCUP00000014644	Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.	Urocortin.	0.999