ERCC4 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ERCC4

ERCC excision repair 4, endonuclease catalytic subunit. (909 aa)

Predicted Functional Partners:

ERCC1

0.999

SLX4

0.997

XPA

0.994

BIVM

0.984

ERCC3

0.975

FAAP24

0.970

ERCC2

0.970

WRN

0.963

FANCC

0.958

FANCF

0.957

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BIVM	ERCC1	ENSOCUP00000010688	ENSOCUP00000024644	Uncharacterized protein.	Uncharacterized protein.	0.964
BIVM	ERCC2	ENSOCUP00000010688	ENSOCUP00000028988	Uncharacterized protein.	ERCC excision repair 2, TFIIH core complex helicase subunit.	0.991
BIVM	ERCC3	ENSOCUP00000010688	ENSOCUP00000001942	Uncharacterized protein.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.995
BIVM	ERCC4	ENSOCUP00000010688	ENSOCUP00000012874	Uncharacterized protein.	ERCC excision repair 4, endonuclease catalytic subunit.	0.984
BIVM	FAAP24	ENSOCUP00000010688	ENSOCUP00000026641	Uncharacterized protein.	FA core complex associated protein 24.	0.784
BIVM	SLX4	ENSOCUP00000010688	ENSOCUP00000006372	Uncharacterized protein.	SLX4 structure-specific endonuclease subunit.	0.620
BIVM	WRN	ENSOCUP00000010688	ENSOCUP00000010872	Uncharacterized protein.	WRN RecQ like helicase.	0.996
BIVM	XPA	ENSOCUP00000010688	ENSOCUP00000011935	Uncharacterized protein.	XPA, DNA damage recognition and repair factor.	0.994
ERCC1	BIVM	ENSOCUP00000024644	ENSOCUP00000010688	Uncharacterized protein.	Uncharacterized protein.	0.964
ERCC1	ERCC2	ENSOCUP00000024644	ENSOCUP00000028988	Uncharacterized protein.	ERCC excision repair 2, TFIIH core complex helicase subunit.	0.964
ERCC1	ERCC3	ENSOCUP00000024644	ENSOCUP00000001942	Uncharacterized protein.	ERCC excision repair 3, TFIIH core complex helicase subunit.	0.955
ERCC1	ERCC4	ENSOCUP00000024644	ENSOCUP00000012874	Uncharacterized protein.	ERCC excision repair 4, endonuclease catalytic subunit.	0.999
ERCC1	FAAP24	ENSOCUP00000024644	ENSOCUP00000026641	Uncharacterized protein.	FA core complex associated protein 24.	0.833
ERCC1	FANCC	ENSOCUP00000024644	ENSOCUP00000009029	Uncharacterized protein.	Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.	0.790
ERCC1	FANCF	ENSOCUP00000024644	ENSOCUP00000007211	Uncharacterized protein.	FA complementation group F.	0.823
ERCC1	SLX4	ENSOCUP00000024644	ENSOCUP00000006372	Uncharacterized protein.	SLX4 structure-specific endonuclease subunit.	0.990
ERCC1	WRN	ENSOCUP00000024644	ENSOCUP00000010872	Uncharacterized protein.	WRN RecQ like helicase.	0.861
ERCC1	XPA	ENSOCUP00000024644	ENSOCUP00000011935	Uncharacterized protein.	XPA, DNA damage recognition and repair factor.	0.997
ERCC2	BIVM	ENSOCUP00000028988	ENSOCUP00000010688	ERCC excision repair 2, TFIIH core complex helicase subunit.	Uncharacterized protein.	0.991
ERCC2	ERCC1	ENSOCUP00000028988	ENSOCUP00000024644	ERCC excision repair 2, TFIIH core complex helicase subunit.	Uncharacterized protein.	0.964