STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OVCH2Ovochymase 2 (gene/pseudogene); Belongs to the peptidase S1 family. (566 aa)    
Predicted Functional Partners:
WFDC13
WAP four-disulfide core domain 13.
    
 0.763
WFDC9
WAP four-disulfide core domain 9.
   
  
 0.737
F5
Coagulation factor V.
    
 0.716
ADAM28
ADAM metallopeptidase domain 28.
   
  
 0.661
G1U804_RABIT
Uncharacterized protein.
    
 0.587
MST1R
Macrophage stimulating 1 receptor.
   
 0.572
MET
Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...]
    
  0.537
TRIB2
Tribbles pseudokinase 2.
   
 
 0.528
LOC100346323
Uncharacterized protein.
    
 0.470
CNTN5
Contactin 5.
   
 
 0.460
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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