STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXW4F-box and WD repeat domain containing 4. (406 aa)    
Predicted Functional Partners:
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.830
FBXW2
F-box and WD repeat domain containing 2.
     
 0.791
CDRT1
WD_REPEATS_REGION domain-containing protein.
     
 0.715
FBXL15
F-box and leucine rich repeat protein 15.
   
 
 0.674
FBXW9
Uncharacterized protein.
     
 0.674
POLL
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
 
 
  
 0.671
FBXW8
F-box and WD repeat domain containing 8.
   
 
 0.668
SKP1
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.633
CUL3
Cullin 3; Belongs to the cullin family.
    
  0.625
SH2D5
SH2 domain containing 5.
      
 0.610
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.