CCK protein (Oryctolagus cuniculus) - STRING interaction network

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Score

CCK

Gastrin domain-containing protein. (115 aa)

Predicted Functional Partners:

CCKBR

0.999

CCKAR

0.999

GHRL

0.930

SST

0.927

GAST

0.923

NTS

0.918

NPY

0.903

PYY

0.902

LOC100345534

0.901

TAC1

0.886

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCK	CCKAR	ENSOCUP00000013458	ENSOCUP00000011577	Gastrin domain-containing protein.	Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	0.999
CCK	CCKBR	ENSOCUP00000013458	ENSOCUP00000006740	Gastrin domain-containing protein.	Gastrin/cholecystokinin type B receptor; Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family.	0.999
CCK	GAST	ENSOCUP00000013458	ENSOCUP00000019850	Gastrin domain-containing protein.	Gastrin.	0.923
CCK	GHRL	ENSOCUP00000013458	ENSOCUP00000029787	Gastrin domain-containing protein.	Uncharacterized protein.	0.930
CCK	LOC100345534	ENSOCUP00000013458	ENSOCUP00000023317	Gastrin domain-containing protein.	Gastrin domain-containing protein.	0.901
CCK	NPY	ENSOCUP00000013458	ENSOCUP00000009261	Gastrin domain-containing protein.	Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.	0.903
CCK	NTS	ENSOCUP00000013458	ENSOCUP00000008901	Gastrin domain-containing protein.	Neurotensin.	0.918
CCK	PYY	ENSOCUP00000013458	ENSOCUP00000011243	Gastrin domain-containing protein.	Peptide YY(3-36); This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.	0.902
CCK	SST	ENSOCUP00000013458	ENSOCUP00000006540	Gastrin domain-containing protein.	Somatostatin.	0.927
CCK	TAC1	ENSOCUP00000013458	ENSOCUP00000037983	Gastrin domain-containing protein.	C-terminal-flanking peptide; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles; Belongs to the tachykinin family.	0.886
CCKAR	CCK	ENSOCUP00000011577	ENSOCUP00000013458	Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	Gastrin domain-containing protein.	0.999
CCKAR	CCKBR	ENSOCUP00000011577	ENSOCUP00000006740	Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	Gastrin/cholecystokinin type B receptor; Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family.	0.935
CCKAR	GAST	ENSOCUP00000011577	ENSOCUP00000019850	Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	Gastrin.	0.946
CCKAR	GHRL	ENSOCUP00000011577	ENSOCUP00000029787	Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	Uncharacterized protein.	0.529
CCKAR	LOC100345534	ENSOCUP00000011577	ENSOCUP00000023317	Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	Gastrin domain-containing protein.	0.999
CCKAR	NPY	ENSOCUP00000011577	ENSOCUP00000009261	Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.	0.589
CCKAR	NTS	ENSOCUP00000011577	ENSOCUP00000008901	Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	Neurotensin.	0.667
CCKAR	PYY	ENSOCUP00000011577	ENSOCUP00000011243	Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	Peptide YY(3-36); This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.	0.641
CCKBR	CCK	ENSOCUP00000006740	ENSOCUP00000013458	Gastrin/cholecystokinin type B receptor; Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family.	Gastrin domain-containing protein.	0.999
CCKBR	CCKAR	ENSOCUP00000006740	ENSOCUP00000011577	Gastrin/cholecystokinin type B receptor; Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family.	Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).	0.935