| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGRP | CCK | ENSOCUP00000010187 | ENSOCUP00000013458 | Agouti related neuropeptide. | Gastrin domain-containing protein. | 0.865 |
| AGRP | CCKAR | ENSOCUP00000010187 | ENSOCUP00000011577 | Agouti related neuropeptide. | Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | 0.482 |
| AGRP | GHRL | ENSOCUP00000010187 | ENSOCUP00000029787 | Agouti related neuropeptide. | Uncharacterized protein. | 0.926 |
| AGRP | NPY | ENSOCUP00000010187 | ENSOCUP00000009261 | Agouti related neuropeptide. | Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | 0.977 |
| AGRP | NTS | ENSOCUP00000010187 | ENSOCUP00000008901 | Agouti related neuropeptide. | Neurotensin. | 0.714 |
| AGRP | OXT | ENSOCUP00000010187 | ENSOCUP00000045888 | Agouti related neuropeptide. | Oxytocin; Belongs to the vasopressin/oxytocin family. | 0.760 |
| AGRP | PYY | ENSOCUP00000010187 | ENSOCUP00000011243 | Agouti related neuropeptide. | Peptide YY(3-36); This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. | 0.755 |
| AGRP | SST | ENSOCUP00000010187 | ENSOCUP00000006540 | Agouti related neuropeptide. | Somatostatin. | 0.721 |
| CCK | AGRP | ENSOCUP00000013458 | ENSOCUP00000010187 | Gastrin domain-containing protein. | Agouti related neuropeptide. | 0.865 |
| CCK | CCKAR | ENSOCUP00000013458 | ENSOCUP00000011577 | Gastrin domain-containing protein. | Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | 0.991 |
| CCK | CCKBR | ENSOCUP00000013458 | ENSOCUP00000006740 | Gastrin domain-containing protein. | Gastrin/cholecystokinin type B receptor; Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. | 0.993 |
| CCK | GAST | ENSOCUP00000013458 | ENSOCUP00000019850 | Gastrin domain-containing protein. | Gastrin. | 0.901 |
| CCK | GHRL | ENSOCUP00000013458 | ENSOCUP00000029787 | Gastrin domain-containing protein. | Uncharacterized protein. | 0.919 |
| CCK | NPY | ENSOCUP00000013458 | ENSOCUP00000009261 | Gastrin domain-containing protein. | Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. | 0.897 |
| CCK | NTS | ENSOCUP00000013458 | ENSOCUP00000008901 | Gastrin domain-containing protein. | Neurotensin. | 0.893 |
| CCK | OXT | ENSOCUP00000013458 | ENSOCUP00000045888 | Gastrin domain-containing protein. | Oxytocin; Belongs to the vasopressin/oxytocin family. | 0.862 |
| CCK | PYY | ENSOCUP00000013458 | ENSOCUP00000011243 | Gastrin domain-containing protein. | Peptide YY(3-36); This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. | 0.906 |
| CCK | SST | ENSOCUP00000013458 | ENSOCUP00000006540 | Gastrin domain-containing protein. | Somatostatin. | 0.916 |
| CCKAR | AGRP | ENSOCUP00000011577 | ENSOCUP00000010187 | Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | Agouti related neuropeptide. | 0.482 |
| CCKAR | CCK | ENSOCUP00000011577 | ENSOCUP00000013458 | Cholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). | Gastrin domain-containing protein. | 0.991 |
