node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F13B | F5 | ENSOCUP00000000898 | ENSOCUP00000025128 | Coagulation factor XIII B chain. | Coagulation factor V. | 0.570 |
F13B | F8 | ENSOCUP00000000898 | ENSOCUP00000049694 | Coagulation factor XIII B chain. | Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family. | 0.479 |
F13B | PROC | ENSOCUP00000000898 | ENSOCUP00000041616 | Coagulation factor XIII B chain. | Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | 0.756 |
F13B | SERPINC1 | ENSOCUP00000000898 | ENSOCUP00000002512 | Coagulation factor XIII B chain. | Serpin family C member 1; Belongs to the serpin family. | 0.807 |
F13B | SERPIND1 | ENSOCUP00000000898 | ENSOCUP00000007813 | Coagulation factor XIII B chain. | Heparin cofactor 2; Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT). | 0.851 |
F3 | F8 | ENSOCUP00000029185 | ENSOCUP00000049694 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family. | 0.562 |
F3 | PROC | ENSOCUP00000029185 | ENSOCUP00000041616 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | 0.781 |
F3 | SERPINC1 | ENSOCUP00000029185 | ENSOCUP00000002512 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | Serpin family C member 1; Belongs to the serpin family. | 0.840 |
F3 | SERPIND1 | ENSOCUP00000029185 | ENSOCUP00000007813 | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | Heparin cofactor 2; Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT). | 0.584 |
F5 | F13B | ENSOCUP00000025128 | ENSOCUP00000000898 | Coagulation factor V. | Coagulation factor XIII B chain. | 0.570 |
F5 | F8 | ENSOCUP00000025128 | ENSOCUP00000049694 | Coagulation factor V. | Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family. | 0.711 |
F5 | PROC | ENSOCUP00000025128 | ENSOCUP00000041616 | Coagulation factor V. | Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | 0.762 |
F5 | PROS1 | ENSOCUP00000025128 | ENSOCUP00000018723 | Coagulation factor V. | Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. | 0.980 |
F5 | SERPINC1 | ENSOCUP00000025128 | ENSOCUP00000002512 | Coagulation factor V. | Serpin family C member 1; Belongs to the serpin family. | 0.574 |
F5 | SERPIND1 | ENSOCUP00000025128 | ENSOCUP00000007813 | Coagulation factor V. | Heparin cofactor 2; Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT). | 0.558 |
F8 | F13B | ENSOCUP00000049694 | ENSOCUP00000000898 | Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family. | Coagulation factor XIII B chain. | 0.479 |
F8 | F3 | ENSOCUP00000049694 | ENSOCUP00000029185 | Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family. | Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. | 0.562 |
F8 | F5 | ENSOCUP00000049694 | ENSOCUP00000025128 | Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family. | Coagulation factor V. | 0.711 |
F8 | PROC | ENSOCUP00000049694 | ENSOCUP00000041616 | Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family. | Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family. | 0.801 |
F8 | PROS1 | ENSOCUP00000049694 | ENSOCUP00000018723 | Coagulation factor VIII isoform a (Predicted); Belongs to the multicopper oxidase family. | Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. | 0.733 |