CHRM2 protein (Oryctolagus cuniculus) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDKRB1	CHRM2	ENSOCUP00000022849	ENSOCUP00000014240	B1 bradykinin receptor; This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.884
CHRM2	BDKRB1	ENSOCUP00000014240	ENSOCUP00000022849	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	B1 bradykinin receptor; This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.	0.884
CHRM2	GNAI2	ENSOCUP00000014240	ENSOCUP00000019624	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein subunit alpha i2.	0.901
CHRM2	GNAO1	ENSOCUP00000014240	ENSOCUP00000040227	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein subunit alpha o1.	0.884
CHRM2	GNB3	ENSOCUP00000014240	ENSOCUP00000011129	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	G protein subunit beta 3.	0.872
CHRM2	GNB5	ENSOCUP00000014240	ENSOCUP00000010220	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.909
CHRM2	GNG11	ENSOCUP00000014240	ENSOCUP00000014632	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.871
CHRM2	GNG4	ENSOCUP00000014240	ENSOCUP00000005907	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.904
CHRM2	LPAR3	ENSOCUP00000014240	ENSOCUP00000022607	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family.	0.874
CHRM2	OXT	ENSOCUP00000014240	ENSOCUP00000045888	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Oxytocin; Belongs to the vasopressin/oxytocin family.	0.883
CHRM2	SST	ENSOCUP00000014240	ENSOCUP00000006540	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	Somatostatin.	0.884
GNAI2	CHRM2	ENSOCUP00000019624	ENSOCUP00000014240	G protein subunit alpha i2.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.901
GNAI2	GNAO1	ENSOCUP00000019624	ENSOCUP00000040227	G protein subunit alpha i2.	G protein subunit alpha o1.	0.982
GNAI2	GNB3	ENSOCUP00000019624	ENSOCUP00000011129	G protein subunit alpha i2.	G protein subunit beta 3.	0.984
GNAI2	GNB5	ENSOCUP00000019624	ENSOCUP00000010220	G protein subunit alpha i2.	Guanine nucleotide-binding protein subunit beta-5; Enhances GTPase-activating protein (GAP) activity of regulator of G protein signaling (RGS) proteins, hence involved in the termination of the signaling initiated by the G protein coupled receptors (GPCRs) by accelerating the GTP hydrolysis on the G-alpha subunits, thereby promoting their inactivation (Probable). Increases RGS9 GTPase-activating protein (GAP) activity, hence contributes to the deactivation of G protein signaling initiated by D(2) dopamine receptors (By similarity). May play an important role in neuronal signaling, incl [...]	0.937
GNAI2	GNG11	ENSOCUP00000019624	ENSOCUP00000014632	G protein subunit alpha i2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.959
GNAI2	GNG4	ENSOCUP00000019624	ENSOCUP00000005907	G protein subunit alpha i2.	Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.977
GNAI2	SST	ENSOCUP00000019624	ENSOCUP00000006540	G protein subunit alpha i2.	Somatostatin.	0.402
GNAO1	CHRM2	ENSOCUP00000040227	ENSOCUP00000014240	G protein subunit alpha o1.	Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.	0.884
GNAO1	GNAI2	ENSOCUP00000040227	ENSOCUP00000019624	G protein subunit alpha o1.	G protein subunit alpha i2.	0.982