LRP1B protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APP	CALR3	ENSOCUP00000009130	ENSOCUP00000011663	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Calreticulin.	0.814
APP	EGFR	ENSOCUP00000009130	ENSOCUP00000009041	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Receptor protein-tyrosine kinase.	0.852
APP	GULP1	ENSOCUP00000009130	ENSOCUP00000046448	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	GULP PTB domain containing engulfment adaptor 1.	0.748
APP	LRP1B	ENSOCUP00000009130	ENSOCUP00000014803	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	LDL receptor related protein 1B.	0.779
APP	LRP2	ENSOCUP00000009130	ENSOCUP00000009497	Gamma-secretase C-terminal fragment 57; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions (By similarity). Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb (By similarity). Couples to apoptosis-inducing pathways such as those medi [...]	Uncharacterized protein.	0.552
C1QA	C1QB	ENSOCUP00000026373	ENSOCUP00000044926	Complement C1q A chain.	Complement C1q B chain.	0.999
C1QA	C1QC	ENSOCUP00000026373	ENSOCUP00000013007	Complement C1q A chain.	Complement C1q C chain.	0.999
C1QA	CALR3	ENSOCUP00000026373	ENSOCUP00000011663	Complement C1q A chain.	Calreticulin.	0.861
C1QA	ENSOCUP00000031621	ENSOCUP00000026373	ENSOCUP00000031621	Complement C1q A chain.	Uncharacterized protein.	0.435
C1QA	LRP1B	ENSOCUP00000026373	ENSOCUP00000014803	Complement C1q A chain.	LDL receptor related protein 1B.	0.861
C1QA	LRP2	ENSOCUP00000026373	ENSOCUP00000009497	Complement C1q A chain.	Uncharacterized protein.	0.435
C1QB	C1QA	ENSOCUP00000044926	ENSOCUP00000026373	Complement C1q B chain.	Complement C1q A chain.	0.999
C1QB	C1QC	ENSOCUP00000044926	ENSOCUP00000013007	Complement C1q B chain.	Complement C1q C chain.	0.999
C1QB	CALR3	ENSOCUP00000044926	ENSOCUP00000011663	Complement C1q B chain.	Calreticulin.	0.868
C1QB	ENSOCUP00000031621	ENSOCUP00000044926	ENSOCUP00000031621	Complement C1q B chain.	Uncharacterized protein.	0.416
C1QB	LRP1B	ENSOCUP00000044926	ENSOCUP00000014803	Complement C1q B chain.	LDL receptor related protein 1B.	0.851
C1QB	LRP2	ENSOCUP00000044926	ENSOCUP00000009497	Complement C1q B chain.	Uncharacterized protein.	0.416
C1QC	C1QA	ENSOCUP00000013007	ENSOCUP00000026373	Complement C1q C chain.	Complement C1q A chain.	0.999
C1QC	C1QB	ENSOCUP00000013007	ENSOCUP00000044926	Complement C1q C chain.	Complement C1q B chain.	0.999
C1QC	CALR3	ENSOCUP00000013007	ENSOCUP00000011663	Complement C1q C chain.	Calreticulin.	0.846