SYK protein (Oryctolagus cuniculus) - STRING interaction network

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Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBL	LAT	ENSOCUP00000004160	ENSOCUP00000017117	Cbl proto-oncogene.	Linker for activation of T cells.	0.708
CBL	LCP2	ENSOCUP00000004160	ENSOCUP00000000465	Cbl proto-oncogene.	Lymphocyte cytosolic protein 2.	0.836
CBL	LYN	ENSOCUP00000004160	ENSOCUP00000002661	Cbl proto-oncogene.	Tyrosine-protein kinase.	0.973
CBL	PLCG1	ENSOCUP00000004160	ENSOCUP00000021041	Cbl proto-oncogene.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.960
CBL	SYK	ENSOCUP00000004160	ENSOCUP00000015068	Cbl proto-oncogene.	Tyrosine-protein kinase.	0.990
CBL	VAV1	ENSOCUP00000004160	ENSOCUP00000022704	Cbl proto-oncogene.	Vav guanine nucleotide exchange factor 1.	0.996
CBL	VAV3	ENSOCUP00000004160	ENSOCUP00000036367	Cbl proto-oncogene.	Vav guanine nucleotide exchange factor 3.	0.802
CD247	FCER1G	ENSOCUP00000027572	ENSOCUP00000033471	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Fc fragment of IgE receptor Ig.	0.679
CD247	LAT	ENSOCUP00000027572	ENSOCUP00000017117	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Linker for activation of T cells.	0.737
CD247	LCP2	ENSOCUP00000027572	ENSOCUP00000000465	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Lymphocyte cytosolic protein 2.	0.838
CD247	LYN	ENSOCUP00000027572	ENSOCUP00000002661	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Tyrosine-protein kinase.	0.631
CD247	PLCG1	ENSOCUP00000027572	ENSOCUP00000021041	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.725
CD247	SYK	ENSOCUP00000027572	ENSOCUP00000015068	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Tyrosine-protein kinase.	0.988
CD247	TYROBP	ENSOCUP00000027572	ENSOCUP00000022343	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	TYRO protein tyrosine kinase binding protein.	0.612
CD247	VAV1	ENSOCUP00000027572	ENSOCUP00000022704	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	Vav guanine nucleotide exchange factor 1.	0.546
FCER1G	CD247	ENSOCUP00000033471	ENSOCUP00000027572	Fc fragment of IgE receptor Ig.	T-cell surface glycoprotein CD3 zeta chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of d [...]	0.679
FCER1G	LAT	ENSOCUP00000033471	ENSOCUP00000017117	Fc fragment of IgE receptor Ig.	Linker for activation of T cells.	0.498
FCER1G	LCP2	ENSOCUP00000033471	ENSOCUP00000000465	Fc fragment of IgE receptor Ig.	Lymphocyte cytosolic protein 2.	0.707
FCER1G	LYN	ENSOCUP00000033471	ENSOCUP00000002661	Fc fragment of IgE receptor Ig.	Tyrosine-protein kinase.	0.931
FCER1G	PLCG1	ENSOCUP00000033471	ENSOCUP00000021041	Fc fragment of IgE receptor Ig.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.510