FFAR2 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FFAR2

Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family. (330 aa)

Predicted Functional Partners:

FFAR4

0.818

GHRL

0.779

PYY

0.750

NPY

0.732

SST

0.729

GPR119

0.694

EDN1

0.675

GNAI1

0.673

GNAI3

0.673

GNAI2

0.673

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDN1	FFAR2	ENSOCUP00000011526	ENSOCUP00000015265	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.675
EDN1	GHRL	ENSOCUP00000011526	ENSOCUP00000029787	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Uncharacterized protein.	0.467
EDN1	GNAI1	ENSOCUP00000011526	ENSOCUP00000000882	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	G protein subunit alpha i1.	0.403
EDN1	NPY	ENSOCUP00000011526	ENSOCUP00000009261	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.	0.426
FFAR2	EDN1	ENSOCUP00000015265	ENSOCUP00000011526	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.675
FFAR2	FFAR4	ENSOCUP00000015265	ENSOCUP00000009065	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	Free fatty acid receptor 4.	0.818
FFAR2	GHRL	ENSOCUP00000015265	ENSOCUP00000029787	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.779
FFAR2	GNAI1	ENSOCUP00000015265	ENSOCUP00000000882	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha i1.	0.673
FFAR2	GNAI2	ENSOCUP00000015265	ENSOCUP00000019624	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha i2.	0.673
FFAR2	GNAI3	ENSOCUP00000015265	ENSOCUP00000004821	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	G protein subunit alpha i3.	0.673
FFAR2	GPR119	ENSOCUP00000015265	ENSOCUP00000010145	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family.	0.694
FFAR2	NPY	ENSOCUP00000015265	ENSOCUP00000009261	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	Neuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.	0.732
FFAR2	PYY	ENSOCUP00000015265	ENSOCUP00000011243	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	Peptide YY(3-36); This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.	0.750
FFAR2	SST	ENSOCUP00000015265	ENSOCUP00000006540	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	Somatostatin.	0.729
FFAR4	FFAR2	ENSOCUP00000009065	ENSOCUP00000015265	Free fatty acid receptor 4.	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.818
FFAR4	GHRL	ENSOCUP00000009065	ENSOCUP00000029787	Free fatty acid receptor 4.	Uncharacterized protein.	0.518
FFAR4	GPR119	ENSOCUP00000009065	ENSOCUP00000010145	Free fatty acid receptor 4.	G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family.	0.702
FFAR4	PYY	ENSOCUP00000009065	ENSOCUP00000011243	Free fatty acid receptor 4.	Peptide YY(3-36); This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.	0.623
GHRL	EDN1	ENSOCUP00000029787	ENSOCUP00000011526	Uncharacterized protein.	Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family.	0.467
GHRL	FFAR2	ENSOCUP00000029787	ENSOCUP00000015265	Uncharacterized protein.	Free fatty acid receptor 2; Belongs to the G-protein coupled receptor 1 family.	0.779