STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DSPPUncharacterized protein. (657 aa)    
Predicted Functional Partners:
UBE2V1
Ubiquitin conjugating enzyme E2 V1.
   
 
 0.950
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
     
 0.935
ITGAV
Integrin subunit alpha V; Belongs to the integrin alpha chain family.
     
  0.933
ITGB6
Integrin beta; Belongs to the integrin beta chain family.
     
 0.913
AUP1
AUP1 lipid droplet regulating VLDL assembly factor.
    
 
 0.882
DMP1
Dentin matrix acidic phosphoprotein 1.
 
 
  
 0.811
SYVN1
Synoviolin 1.
    
 
 0.787
AMFR
Autocrine motility factor receptor.
    
 
 0.787
CNOT2
CCR4-NOT transcription complex subunit 2.
    
 
 0.766
UBA1
Ubiquitin-like modifier-activating enzyme 1; Catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation through the ubiquitin-proteasome system. Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP. Essential for the formation of radiation-induced foci, timely DNA repair and for response to replication stress. Promotes the recruitment of TP53BP1 and BRCA1 at DNA damage sites (By similarity).
    
 0.762
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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