node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1R | C1S | ENSOCUP00000029177 | ENSOCUP00000012442 | Complement C1r; Belongs to the peptidase S1 family. | Complement C1s; Belongs to the peptidase S1 family. | 0.999 |
C1R | CD55 | ENSOCUP00000029177 | ENSOCUP00000045061 | Complement C1r; Belongs to the peptidase S1 family. | Uncharacterized protein. | 0.704 |
C1R | CD59 | ENSOCUP00000029177 | ENSOCUP00000036438 | Complement C1r; Belongs to the peptidase S1 family. | CD59 glycoprotein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. | 0.701 |
C1R | CLUL1 | ENSOCUP00000029177 | ENSOCUP00000007480 | Complement C1r; Belongs to the peptidase S1 family. | Clusterin; Belongs to the clusterin family. | 0.567 |
C1R | LOC100341359 | ENSOCUP00000029177 | ENSOCUP00000010460 | Complement C1r; Belongs to the peptidase S1 family. | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. | 0.668 |
C1R | MBL2 | ENSOCUP00000029177 | ENSOCUP00000010961 | Complement C1r; Belongs to the peptidase S1 family. | Mannose binding lectin 2. | 0.868 |
C1R | VTN | ENSOCUP00000029177 | ENSOCUP00000024132 | Complement C1r; Belongs to the peptidase S1 family. | Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. | 0.605 |
C1S | C1R | ENSOCUP00000012442 | ENSOCUP00000029177 | Complement C1s; Belongs to the peptidase S1 family. | Complement C1r; Belongs to the peptidase S1 family. | 0.999 |
C1S | CD55 | ENSOCUP00000012442 | ENSOCUP00000045061 | Complement C1s; Belongs to the peptidase S1 family. | Uncharacterized protein. | 0.722 |
C1S | CD59 | ENSOCUP00000012442 | ENSOCUP00000036438 | Complement C1s; Belongs to the peptidase S1 family. | CD59 glycoprotein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. | 0.706 |
C1S | CLUL1 | ENSOCUP00000012442 | ENSOCUP00000007480 | Complement C1s; Belongs to the peptidase S1 family. | Clusterin; Belongs to the clusterin family. | 0.545 |
C1S | LOC100341359 | ENSOCUP00000012442 | ENSOCUP00000010460 | Complement C1s; Belongs to the peptidase S1 family. | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. | 0.640 |
C1S | MBL2 | ENSOCUP00000012442 | ENSOCUP00000010961 | Complement C1s; Belongs to the peptidase S1 family. | Mannose binding lectin 2. | 0.867 |
C1S | VTN | ENSOCUP00000012442 | ENSOCUP00000024132 | Complement C1s; Belongs to the peptidase S1 family. | Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. | 0.608 |
C9 | CD59 | ENSOCUP00000010939 | ENSOCUP00000036438 | Complement component C9; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. | CD59 glycoprotein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. | 0.824 |
C9 | CLUL1 | ENSOCUP00000010939 | ENSOCUP00000007480 | Complement component C9; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. | Clusterin; Belongs to the clusterin family. | 0.589 |
C9 | MBL2 | ENSOCUP00000010939 | ENSOCUP00000010961 | Complement component C9; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. | Mannose binding lectin 2. | 0.515 |
C9 | VTN | ENSOCUP00000010939 | ENSOCUP00000024132 | Complement component C9; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC. | Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. | 0.841 |
CD44 | CD55 | ENSOCUP00000048202 | ENSOCUP00000045061 | CD44 molecule (Indian blood group). | Uncharacterized protein. | 0.607 |
CD44 | CD59 | ENSOCUP00000048202 | ENSOCUP00000036438 | CD44 molecule (Indian blood group). | CD59 glycoprotein; Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. | 0.734 |