| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD3E | ENSOCUP00000033540 | ENSOCUP00000019523 | ENSOCUP00000033540 | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] | Ig-like domain-containing protein. | 0.547 |
| CD3E | GRAP2 | ENSOCUP00000019523 | ENSOCUP00000010557 | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] | GRB2 related adaptor protein 2. | 0.566 |
| CD3E | LAT | ENSOCUP00000019523 | ENSOCUP00000017117 | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] | Linker for activation of T cells. | 0.941 |
| CD3E | LCP2 | ENSOCUP00000019523 | ENSOCUP00000000465 | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] | Lymphocyte cytosolic protein 2. | 0.589 |
| CD3E | PIK3R1 | ENSOCUP00000019523 | ENSOCUP00000004433 | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] | Phosphoinositide-3-kinase regulatory subunit 1. | 0.501 |
| CD3E | SYK | ENSOCUP00000019523 | ENSOCUP00000015068 | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] | Tyrosine-protein kinase. | 0.957 |
| CD3E | ZAP70 | ENSOCUP00000019523 | ENSOCUP00000005043 | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] | Tyrosine-protein kinase. | 0.992 |
| ENSOCUP00000033540 | CD3E | ENSOCUP00000033540 | ENSOCUP00000019523 | Ig-like domain-containing protein. | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] | 0.547 |
| ENSOCUP00000033540 | GRAP2 | ENSOCUP00000033540 | ENSOCUP00000010557 | Ig-like domain-containing protein. | GRB2 related adaptor protein 2. | 0.441 |
| ENSOCUP00000033540 | LAT | ENSOCUP00000033540 | ENSOCUP00000017117 | Ig-like domain-containing protein. | Linker for activation of T cells. | 0.941 |
| ENSOCUP00000033540 | LCP2 | ENSOCUP00000033540 | ENSOCUP00000000465 | Ig-like domain-containing protein. | Lymphocyte cytosolic protein 2. | 0.528 |
| ENSOCUP00000033540 | PIK3R1 | ENSOCUP00000033540 | ENSOCUP00000004433 | Ig-like domain-containing protein. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.501 |
| ENSOCUP00000033540 | SYK | ENSOCUP00000033540 | ENSOCUP00000015068 | Ig-like domain-containing protein. | Tyrosine-protein kinase. | 0.951 |
| ENSOCUP00000033540 | ZAP70 | ENSOCUP00000033540 | ENSOCUP00000005043 | Ig-like domain-containing protein. | Tyrosine-protein kinase. | 0.986 |
| GRAP2 | CD3E | ENSOCUP00000010557 | ENSOCUP00000019523 | GRB2 related adaptor protein 2. | T-cell surface glycoprotein CD3 epsilon chain; Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR- mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation o [...] | 0.566 |
| GRAP2 | ENSOCUP00000033540 | ENSOCUP00000010557 | ENSOCUP00000033540 | GRB2 related adaptor protein 2. | Ig-like domain-containing protein. | 0.441 |
| GRAP2 | GRB2 | ENSOCUP00000010557 | ENSOCUP00000042433 | GRB2 related adaptor protein 2. | Growth factor receptor bound protein 2. | 0.723 |
| GRAP2 | LAT | ENSOCUP00000010557 | ENSOCUP00000017117 | GRB2 related adaptor protein 2. | Linker for activation of T cells. | 0.983 |
| GRAP2 | LCP2 | ENSOCUP00000010557 | ENSOCUP00000000465 | GRB2 related adaptor protein 2. | Lymphocyte cytosolic protein 2. | 0.998 |
| GRAP2 | PIK3R1 | ENSOCUP00000010557 | ENSOCUP00000004433 | GRB2 related adaptor protein 2. | Phosphoinositide-3-kinase regulatory subunit 1. | 0.605 |
