node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BGN | COL1A2 | ENSOCUP00000026470 | ENSOCUP00000010575 | Biglycan; May be involved in collagen fiber assembly. | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | 0.875 |
BGN | DCN | ENSOCUP00000026470 | ENSOCUP00000006027 | Biglycan; May be involved in collagen fiber assembly. | Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | 0.951 |
BGN | FN1 | ENSOCUP00000026470 | ENSOCUP00000008718 | Biglycan; May be involved in collagen fiber assembly. | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). | 0.852 |
BGN | LUM | ENSOCUP00000026470 | ENSOCUP00000004852 | Biglycan; May be involved in collagen fiber assembly. | Lumican. | 0.811 |
BGN | TGFBI | ENSOCUP00000026470 | ENSOCUP00000040013 | Biglycan; May be involved in collagen fiber assembly. | Transforming growth factor-beta-induced protein ig-h3; Plays a role in cell adhesion (By similarity). May play a role in cell-collagen interactions (By similarity). | 0.568 |
BGN | THBS1 | ENSOCUP00000026470 | ENSOCUP00000003290 | Biglycan; May be involved in collagen fiber assembly. | Thrombospondin 1. | 0.588 |
BGN | VTN | ENSOCUP00000026470 | ENSOCUP00000024132 | Biglycan; May be involved in collagen fiber assembly. | Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. | 0.563 |
COL1A2 | BGN | ENSOCUP00000010575 | ENSOCUP00000026470 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Biglycan; May be involved in collagen fiber assembly. | 0.875 |
COL1A2 | DCN | ENSOCUP00000010575 | ENSOCUP00000006027 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | 0.883 |
COL1A2 | FN1 | ENSOCUP00000010575 | ENSOCUP00000008718 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). | 0.847 |
COL1A2 | LUM | ENSOCUP00000010575 | ENSOCUP00000004852 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Lumican. | 0.984 |
COL1A2 | TGFBI | ENSOCUP00000010575 | ENSOCUP00000040013 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Transforming growth factor-beta-induced protein ig-h3; Plays a role in cell adhesion (By similarity). May play a role in cell-collagen interactions (By similarity). | 0.533 |
COL1A2 | THBS1 | ENSOCUP00000010575 | ENSOCUP00000003290 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | Thrombospondin 1. | 0.565 |
DCN | BGN | ENSOCUP00000006027 | ENSOCUP00000026470 | Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Biglycan; May be involved in collagen fiber assembly. | 0.951 |
DCN | COL1A2 | ENSOCUP00000006027 | ENSOCUP00000010575 | Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. | 0.883 |
DCN | FN1 | ENSOCUP00000006027 | ENSOCUP00000008718 | Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). | 0.929 |
DCN | LUM | ENSOCUP00000006027 | ENSOCUP00000004852 | Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Lumican. | 0.949 |
DCN | TGFBI | ENSOCUP00000006027 | ENSOCUP00000040013 | Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Transforming growth factor-beta-induced protein ig-h3; Plays a role in cell adhesion (By similarity). May play a role in cell-collagen interactions (By similarity). | 0.626 |
DCN | THBS1 | ENSOCUP00000006027 | ENSOCUP00000003290 | Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Thrombospondin 1. | 0.771 |
DCN | VTN | ENSOCUP00000006027 | ENSOCUP00000024132 | Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. | Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. | 0.860 |