node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCL2 | GPX1 | ENSOCUP00000036189 | ENSOCUP00000005141 | BH4_2 domain-containing protein. | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | 0.759 |
BCL2 | HSPA5 | ENSOCUP00000036189 | ENSOCUP00000029180 | BH4_2 domain-containing protein. | Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. | 0.509 |
BCL2 | SOD1 | ENSOCUP00000036189 | ENSOCUP00000017459 | BH4_2 domain-containing protein. | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. | 0.968 |
BCL2 | VDAC1 | ENSOCUP00000036189 | ENSOCUP00000008083 | BH4_2 domain-containing protein. | Voltage-dependent anion-selective channel protein 1; Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition p [...] | 0.812 |
CAT | GPX1 | ENSOCUP00000027899 | ENSOCUP00000005141 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | 0.532 |
CAT | PARK7 | ENSOCUP00000027899 | ENSOCUP00000039196 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. | Parkinsonism associated deglycase. | 0.724 |
CAT | SOD1 | ENSOCUP00000027899 | ENSOCUP00000017459 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. | 0.926 |
CCS | GPX1 | ENSOCUP00000011889 | ENSOCUP00000005141 | Copper chaperone for superoxide dismutase. | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | 0.586 |
CCS | SOD1 | ENSOCUP00000011889 | ENSOCUP00000017459 | Copper chaperone for superoxide dismutase. | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. | 0.966 |
DERL1 | HSPA5 | ENSOCUP00000007871 | ENSOCUP00000029180 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. | 0.976 |
DERL1 | SOD1 | ENSOCUP00000007871 | ENSOCUP00000017459 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. | 0.912 |
GPX1 | BCL2 | ENSOCUP00000005141 | ENSOCUP00000036189 | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | BH4_2 domain-containing protein. | 0.759 |
GPX1 | CAT | ENSOCUP00000005141 | ENSOCUP00000027899 | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. | 0.532 |
GPX1 | CCS | ENSOCUP00000005141 | ENSOCUP00000011889 | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | Copper chaperone for superoxide dismutase. | 0.586 |
GPX1 | PARK7 | ENSOCUP00000005141 | ENSOCUP00000039196 | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | Parkinsonism associated deglycase. | 0.415 |
GPX1 | PPARGC1A | ENSOCUP00000005141 | ENSOCUP00000034883 | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | PPARG coactivator 1 alpha. | 0.929 |
GPX1 | SOD1 | ENSOCUP00000005141 | ENSOCUP00000017459 | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. | 0.922 |
HSPA5 | BCL2 | ENSOCUP00000029180 | ENSOCUP00000036189 | Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. | BH4_2 domain-containing protein. | 0.509 |
HSPA5 | DERL1 | ENSOCUP00000029180 | ENSOCUP00000007871 | Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.976 |
HSPA5 | SOD1 | ENSOCUP00000029180 | ENSOCUP00000017459 | Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the Cu-Zn superoxide dismutase family. | 0.947 |