STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WFDC5WAP four-disulfide core domain 5. (122 aa)    
Predicted Functional Partners:
TMEM42
Transmembrane protein 42.
   
  
 0.732
ADGRF4
Adhesion G protein-coupled receptor F4; Belongs to the G-protein coupled receptor 2 family.
      
 0.729
TMEM45A
Transmembrane protein 45A.
      
 0.654
CDHR1
Cadherin related family member 1.
   
  
 0.645
HPSE2
Heparanase 2 (inactive).
      
 0.628
AMTN
Amelotin.
   
  
 0.566
SLC47A1
Multidrug and toxin extrusion protein 1; Solute transporter for tetraethylammonium (TEA), 1-methyl-4- phenylpyridinium (MPP), cimetidine, procainamide. Responsible for the secretion of cationic drugs across the brush border membranes.
   
  
 0.545
THRSP
Uncharacterized protein.
      
 0.509
LOXL4
Lysyl oxidase like 4.
    
 
 0.483
CNMD
Leukocyte cell-derived chemotaxin 1; Bifunctional growth regulator that stimulates the growth of cultured chondrocytes in the presence of basic fibroblast growth factor (FGF) but inhibits the growth of cultured vascular endothelial cells. May contribute to the rapid growth of cartilage and vascular invasion prior to the replacement of cartilage by bone during endochondral bone development. Inhibits in vitro tube formation and mobilization of endothelial cells. Plays a role as antiangiogenic factor in cardiac valves to suppress neovascularization (By similarity); Belongs to the chondrom [...]
   
  
 0.468
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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