TMPRSS2 protein (Oryctolagus cuniculus) - STRING interaction network

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Score

TMPRSS2

Transmembrane serine protease 2; Belongs to the peptidase S1 family. (612 aa)

Predicted Functional Partners:

ACE2

0.978

AR

0.935

FURIN

0.896

CTSV

0.857

LOC100356256

0.847

LOC100347623

0.846

LOC100344030

0.846

ETV1

0.831

CD9

0.820

ERG

0.797

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACE2	CTSV	ENSOCUP00000015275	ENSOCUP00000038389	Angiotensin-converting enzyme.	Cathepsin V; Belongs to the peptidase C1 family.	0.756
ACE2	FURIN	ENSOCUP00000015275	ENSOCUP00000029858	Angiotensin-converting enzyme.	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	0.871
ACE2	LOC100344030	ENSOCUP00000015275	ENSOCUP00000026218	Angiotensin-converting enzyme.	Uncharacterized protein; Belongs to the peptidase C1 family.	0.732
ACE2	LOC100347623	ENSOCUP00000015275	ENSOCUP00000014610	Angiotensin-converting enzyme.	Uncharacterized protein; Belongs to the peptidase C1 family.	0.732
ACE2	LOC100356256	ENSOCUP00000015275	ENSOCUP00000015334	Angiotensin-converting enzyme.	Uncharacterized protein; Belongs to the peptidase C1 family.	0.732
ACE2	TMPRSS2	ENSOCUP00000015275	ENSOCUP00000018355	Angiotensin-converting enzyme.	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	0.978
AR	ERG	ENSOCUP00000042647	ENSOCUP00000047192	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	ETS transcription factor ERG.	0.648
AR	ETV1	ENSOCUP00000042647	ENSOCUP00000037357	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	ETS variant 1.	0.796
AR	TMPRSS2	ENSOCUP00000042647	ENSOCUP00000018355	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	0.935
CD9	FURIN	ENSOCUP00000045374	ENSOCUP00000029858	Tetraspanin.	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	0.640
CD9	TMPRSS2	ENSOCUP00000045374	ENSOCUP00000018355	Tetraspanin.	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	0.820
CTSV	ACE2	ENSOCUP00000038389	ENSOCUP00000015275	Cathepsin V; Belongs to the peptidase C1 family.	Angiotensin-converting enzyme.	0.756
CTSV	FURIN	ENSOCUP00000038389	ENSOCUP00000029858	Cathepsin V; Belongs to the peptidase C1 family.	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	0.807
CTSV	TMPRSS2	ENSOCUP00000038389	ENSOCUP00000018355	Cathepsin V; Belongs to the peptidase C1 family.	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	0.857
ERG	AR	ENSOCUP00000047192	ENSOCUP00000042647	ETS transcription factor ERG.	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	0.648
ERG	TMPRSS2	ENSOCUP00000047192	ENSOCUP00000018355	ETS transcription factor ERG.	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	0.797
ETV1	AR	ENSOCUP00000037357	ENSOCUP00000042647	ETS variant 1.	Androgen receptor; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.	0.796
ETV1	TMPRSS2	ENSOCUP00000037357	ENSOCUP00000018355	ETS variant 1.	Transmembrane serine protease 2; Belongs to the peptidase S1 family.	0.831
FURIN	ACE2	ENSOCUP00000029858	ENSOCUP00000015275	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Angiotensin-converting enzyme.	0.871
FURIN	CD9	ENSOCUP00000029858	ENSOCUP00000045374	Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family.	Tetraspanin.	0.640