ZYX protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ZYX

Zyxin. (572 aa)

Predicted Functional Partners:

VASP

0.998

TLN1

0.997

TLN2

0.995

VCL

0.995

PXN

0.966

LASP1

0.879

ENAH

0.812

ILK

0.805

FLNA

0.782

LOC100356070

0.775

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENAH	LOC100356070	ENSOCUP00000001984	ENSOCUP00000019216	ENAH actin regulator.	Profilin; Belongs to the profilin family.	0.484
ENAH	VASP	ENSOCUP00000001984	ENSOCUP00000029878	ENAH actin regulator.	WH1 domain-containing protein.	0.971
ENAH	ZYX	ENSOCUP00000001984	ENSOCUP00000018567	ENAH actin regulator.	Zyxin.	0.812
FLNA	ILK	ENSOCUP00000000761	ENSOCUP00000046462	Uncharacterized protein.	Integrin linked kinase.	0.791
FLNA	LOC100356070	ENSOCUP00000000761	ENSOCUP00000019216	Uncharacterized protein.	Profilin; Belongs to the profilin family.	0.771
FLNA	PXN	ENSOCUP00000000761	ENSOCUP00000034749	Uncharacterized protein.	Paxillin.	0.931
FLNA	TLN1	ENSOCUP00000000761	ENSOCUP00000008817	Uncharacterized protein.	Talin 1.	0.991
FLNA	TLN2	ENSOCUP00000000761	ENSOCUP00000011268	Uncharacterized protein.	Talin 2.	0.988
FLNA	VASP	ENSOCUP00000000761	ENSOCUP00000029878	Uncharacterized protein.	WH1 domain-containing protein.	0.685
FLNA	VCL	ENSOCUP00000000761	ENSOCUP00000039299	Uncharacterized protein.	Vinculin.	0.994
FLNA	ZYX	ENSOCUP00000000761	ENSOCUP00000018567	Uncharacterized protein.	Zyxin.	0.782
ILK	FLNA	ENSOCUP00000046462	ENSOCUP00000000761	Integrin linked kinase.	Uncharacterized protein.	0.791
ILK	PXN	ENSOCUP00000046462	ENSOCUP00000034749	Integrin linked kinase.	Paxillin.	0.989
ILK	TLN1	ENSOCUP00000046462	ENSOCUP00000008817	Integrin linked kinase.	Talin 1.	0.988
ILK	TLN2	ENSOCUP00000046462	ENSOCUP00000011268	Integrin linked kinase.	Talin 2.	0.985
ILK	VASP	ENSOCUP00000046462	ENSOCUP00000029878	Integrin linked kinase.	WH1 domain-containing protein.	0.543
ILK	VCL	ENSOCUP00000046462	ENSOCUP00000039299	Integrin linked kinase.	Vinculin.	0.977
ILK	ZYX	ENSOCUP00000046462	ENSOCUP00000018567	Integrin linked kinase.	Zyxin.	0.805
LASP1	PXN	ENSOCUP00000026760	ENSOCUP00000034749	LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).	Paxillin.	0.421
LASP1	VASP	ENSOCUP00000026760	ENSOCUP00000029878	LIM and SH3 domain protein 1; Plays an important role in the regulation of dynamic actin- based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity).	WH1 domain-containing protein.	0.895