| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AGXT | BHMT | ENSOCUP00000022506 | ENSOCUP00000031900 | Serine--pyruvate aminotransferase. | Hcy-binding domain-containing protein. | 0.773 |
| AGXT | CTH | ENSOCUP00000022506 | ENSOCUP00000006510 | Serine--pyruvate aminotransferase. | Cystathionine gamma-lyase. | 0.551 |
| AGXT | G1U159_RABIT | ENSOCUP00000022506 | ENSOCUP00000023092 | Serine--pyruvate aminotransferase. | Beta_elim_lyase domain-containing protein. | 0.909 |
| AGXT | MTR | ENSOCUP00000022506 | ENSOCUP00000008420 | Serine--pyruvate aminotransferase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.665 |
| AGXT | PSPH | ENSOCUP00000022506 | ENSOCUP00000025907 | Serine--pyruvate aminotransferase. | Phosphoserine phosphatase. | 0.922 |
| AGXT | SDS | ENSOCUP00000022506 | ENSOCUP00000018669 | Serine--pyruvate aminotransferase. | Serine dehydratase. | 0.919 |
| AGXT | SHMT1 | ENSOCUP00000022506 | ENSOCUP00000017814 | Serine--pyruvate aminotransferase. | Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.944 |
| AGXT | SHMT2 | ENSOCUP00000022506 | ENSOCUP00000019769 | Serine--pyruvate aminotransferase. | Serine hydroxymethyltransferase, mitochondrial; Catalyzes the cleavage of serine to glycine accompanied with the production of 5,10-methylenetetrahydrofolate, an essential intermediate for purine biosynthesis. Serine provides the major source of folate one-carbon in cells by catalyzing the transfer of one carbon from serine to tetrahydrofolate. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway via its role in glycine and tetrahydrofolate metabolism: thymidylate biosynthesis is required to prevent uracil accumulation in mtDNA. Also required for mitochondrial tran [...] | 0.920 |
| BCAT1 | BCAT2 | ENSOCUP00000033736 | ENSOCUP00000022965 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Branched chain amino acid transaminase 2. | 0.851 |
| BCAT1 | BHMT | ENSOCUP00000033736 | ENSOCUP00000031900 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Hcy-binding domain-containing protein. | 0.484 |
| BCAT1 | CTH | ENSOCUP00000033736 | ENSOCUP00000006510 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Cystathionine gamma-lyase. | 0.891 |
| BCAT1 | MTR | ENSOCUP00000033736 | ENSOCUP00000008420 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.484 |
| BCAT1 | PSPH | ENSOCUP00000033736 | ENSOCUP00000025907 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Phosphoserine phosphatase. | 0.581 |
| BCAT1 | SDS | ENSOCUP00000033736 | ENSOCUP00000018669 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Serine dehydratase. | 0.922 |
| BCAT1 | SHMT1 | ENSOCUP00000033736 | ENSOCUP00000017814 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.442 |
| BCAT1 | SHMT2 | ENSOCUP00000033736 | ENSOCUP00000019769 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Serine hydroxymethyltransferase, mitochondrial; Catalyzes the cleavage of serine to glycine accompanied with the production of 5,10-methylenetetrahydrofolate, an essential intermediate for purine biosynthesis. Serine provides the major source of folate one-carbon in cells by catalyzing the transfer of one carbon from serine to tetrahydrofolate. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway via its role in glycine and tetrahydrofolate metabolism: thymidylate biosynthesis is required to prevent uracil accumulation in mtDNA. Also required for mitochondrial tran [...] | 0.499 |
| BCAT2 | BCAT1 | ENSOCUP00000022965 | ENSOCUP00000033736 | Branched chain amino acid transaminase 2. | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.851 |
| BCAT2 | BHMT | ENSOCUP00000022965 | ENSOCUP00000031900 | Branched chain amino acid transaminase 2. | Hcy-binding domain-containing protein. | 0.484 |
| BCAT2 | CTH | ENSOCUP00000022965 | ENSOCUP00000006510 | Branched chain amino acid transaminase 2. | Cystathionine gamma-lyase. | 0.891 |
| BCAT2 | MTR | ENSOCUP00000022965 | ENSOCUP00000008420 | Branched chain amino acid transaminase 2. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.484 |
