STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CALUCalumenin; Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma- carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity). May modulate calcium release from the sarcoplasmic reticulum; Belongs to the CREC family. (358 aa)    
Predicted Functional Partners:
CALR
Calreticulin.
   
 
 0.843
CALR3
Calreticulin.
   
 
 0.830
PDIA3
Protein disulfide-isomerase.
   
 
 0.673
IGHA_RABIT
Ig alpha chain C region; Ig alpha is the major immunoglobulin class in body secretions. It may serve both to defend against local infection and to prevent access of foreign antigens to the general immunologic system.
      
 0.567
FAM20B
FAM20B glycosaminoglycan xylosylkinase.
   
 
 0.566
NUCB1
Nucleobindin 1.
   
 
 0.518
FAM20A
FAM20A golgi associated secretory pathway pseudokinase.
     
 0.516
G1T067_RABIT
Fam20C domain-containing protein.
    
 0.502
SUGCT
Succinyl-CoA:glutarate-CoA transferase.
      
 0.473
TMX1
Thioredoxin related transmembrane protein 1.
   
 
 0.468
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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