NKX2-2 protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FOXA2	INS	ENSOCUP00000006365	ENSOCUP00000020463	Forkhead box A2.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.764
FOXA2	ISL1	ENSOCUP00000006365	ENSOCUP00000020036	Forkhead box A2.	ISL LIM homeobox 1.	0.720
FOXA2	NEUROG2	ENSOCUP00000006365	ENSOCUP00000023570	Forkhead box A2.	Neurogenin 2.	0.431
FOXA2	NKX2-2	ENSOCUP00000006365	ENSOCUP00000019073	Forkhead box A2.	NK2 homeobox 2.	0.704
FOXA2	NKX6-1	ENSOCUP00000006365	ENSOCUP00000019963	Forkhead box A2.	NK6 homeobox 1.	0.629
FOXA2	PAX4	ENSOCUP00000006365	ENSOCUP00000001386	Forkhead box A2.	Paired box 4.	0.802
FOXA2	PAX6	ENSOCUP00000006365	ENSOCUP00000019685	Forkhead box A2.	Uncharacterized protein.	0.911
FOXA2	RFX6	ENSOCUP00000006365	ENSOCUP00000011388	Forkhead box A2.	Regulatory factor X6.	0.488
INS	FOXA2	ENSOCUP00000020463	ENSOCUP00000006365	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Forkhead box A2.	0.764
INS	ISL1	ENSOCUP00000020463	ENSOCUP00000020036	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	ISL LIM homeobox 1.	0.612
INS	NEUROG2	ENSOCUP00000020463	ENSOCUP00000023570	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Neurogenin 2.	0.541
INS	NKX2-2	ENSOCUP00000020463	ENSOCUP00000019073	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	NK2 homeobox 2.	0.688
INS	NKX6-1	ENSOCUP00000020463	ENSOCUP00000019963	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	NK6 homeobox 1.	0.616
INS	PAX4	ENSOCUP00000020463	ENSOCUP00000001386	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Paired box 4.	0.893
INS	PAX6	ENSOCUP00000020463	ENSOCUP00000019685	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.894
INS	RFX6	ENSOCUP00000020463	ENSOCUP00000011388	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Regulatory factor X6.	0.715
ISL1	FOXA2	ENSOCUP00000020036	ENSOCUP00000006365	ISL LIM homeobox 1.	Forkhead box A2.	0.720
ISL1	INS	ENSOCUP00000020036	ENSOCUP00000020463	ISL LIM homeobox 1.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.612
ISL1	NEUROG2	ENSOCUP00000020036	ENSOCUP00000023570	ISL LIM homeobox 1.	Neurogenin 2.	0.774
ISL1	NKX2-2	ENSOCUP00000020036	ENSOCUP00000019073	ISL LIM homeobox 1.	NK2 homeobox 2.	0.716