Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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co-expression
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gene co-occurrence
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PNPLA8Calcium-independent phospholipase A2-gamma; Calcium-independent phospholipase A2, which catalyzes the hydrolysis of the sn-2 position of glycerophospholipids, PtdSer and to a lower extent PtdCho. Cleaves membrane phospholipids (By similarity). (778 aa)    
Predicted Functional Partners:
LOC100351425
Phospholipase A(2).
     
 0.865
PNPLA1
Patatin like phospholipase domain containing 1.
      
 0.838
LOC100344166
Phospholipase A(2).
     
 0.829
PNPLA7
Patatin like phospholipase domain containing 7.
   
  
 0.742
PLA2G2C
Phospholipase A(2).
     
 0.731
PLA2G2A
Phospholipase A2, membrane associated; Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins. Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1. Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1. Induces cell proliferat [...]
     
 0.730
PLA2G4C
PLA2c domain-containing protein.
     
 0.728
PLA2G5
Phospholipase A(2).
     
 0.724
PLA2G10
Phospholipase A(2).
     
 0.720
PLA2G10-2
Phospholipase A(2).
     
 0.720
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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