GCG protein (Oryctolagus cuniculus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GCG	GHRL	ENSOCUP00000019727	ENSOCUP00000029787	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Uncharacterized protein.	0.950
GCG	GIP	ENSOCUP00000019727	ENSOCUP00000003809	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Gastric inhibitory polypeptide.	0.910
GCG	GIPR	ENSOCUP00000019727	ENSOCUP00000010218	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family.	0.968
GCG	GLP1R	ENSOCUP00000019727	ENSOCUP00000041020	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	0.995
GCG	GLP2R	ENSOCUP00000019727	ENSOCUP00000040108	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Glucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family.	0.962
GCG	GPR119	ENSOCUP00000019727	ENSOCUP00000010145	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family.	0.921
GCG	INS	ENSOCUP00000019727	ENSOCUP00000020463	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.962
GCG	LEP	ENSOCUP00000019727	ENSOCUP00000008782	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.933
GCG	PPY	ENSOCUP00000019727	ENSOCUP00000025326	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Pancreatic hormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family.	0.909
GCG	SST	ENSOCUP00000019727	ENSOCUP00000006540	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Somatostatin.	0.931
GHRL	GCG	ENSOCUP00000029787	ENSOCUP00000019727	Uncharacterized protein.	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	0.950
GHRL	GIP	ENSOCUP00000029787	ENSOCUP00000003809	Uncharacterized protein.	Gastric inhibitory polypeptide.	0.756
GHRL	GLP1R	ENSOCUP00000029787	ENSOCUP00000041020	Uncharacterized protein.	Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.	0.615
GHRL	INS	ENSOCUP00000029787	ENSOCUP00000020463	Uncharacterized protein.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.982
GHRL	LEP	ENSOCUP00000029787	ENSOCUP00000008782	Uncharacterized protein.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.982
GHRL	PPY	ENSOCUP00000029787	ENSOCUP00000025326	Uncharacterized protein.	Pancreatic hormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family.	0.877
GHRL	SST	ENSOCUP00000029787	ENSOCUP00000006540	Uncharacterized protein.	Somatostatin.	0.877
GIP	GCG	ENSOCUP00000003809	ENSOCUP00000019727	Gastric inhibitory polypeptide.	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	0.910
GIP	GHRL	ENSOCUP00000003809	ENSOCUP00000029787	Gastric inhibitory polypeptide.	Uncharacterized protein.	0.756
GIP	GIPR	ENSOCUP00000003809	ENSOCUP00000010218	Gastric inhibitory polypeptide.	Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family.	0.996