node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADORA2A | GCG | ENSOCUP00000007521 | ENSOCUP00000019727 | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). | 0.935 |
GCG | ADORA2A | ENSOCUP00000019727 | ENSOCUP00000007521 | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. | 0.935 |
GCG | GHRL | ENSOCUP00000019727 | ENSOCUP00000029787 | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). | Uncharacterized protein. | 0.932 |
GCG | GIPR | ENSOCUP00000019727 | ENSOCUP00000010218 | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). | Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. | 0.926 |
GCG | GLP1R | ENSOCUP00000019727 | ENSOCUP00000041020 | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). | Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. | 0.992 |
GCG | GLP2R | ENSOCUP00000019727 | ENSOCUP00000040108 | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). | Glucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. | 0.991 |
GCG | GPR119 | ENSOCUP00000019727 | ENSOCUP00000010145 | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). | G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. | 0.975 |
GCG | IDE | ENSOCUP00000019727 | ENSOCUP00000030432 | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). | Insulin degrading enzyme; Belongs to the peptidase M16 family. | 0.929 |
GCG | INS | ENSOCUP00000019727 | ENSOCUP00000020463 | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.958 |
GCG | SST | ENSOCUP00000019727 | ENSOCUP00000006540 | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). | Somatostatin. | 0.949 |
GCG | VIPR2 | ENSOCUP00000019727 | ENSOCUP00000003013 | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). | Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family. | 0.947 |
GHRL | GCG | ENSOCUP00000029787 | ENSOCUP00000019727 | Uncharacterized protein. | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). | 0.932 |
GHRL | GLP1R | ENSOCUP00000029787 | ENSOCUP00000041020 | Uncharacterized protein. | Glucagon like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family. | 0.650 |
GHRL | GPR119 | ENSOCUP00000029787 | ENSOCUP00000010145 | Uncharacterized protein. | G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. | 0.429 |
GHRL | INS | ENSOCUP00000029787 | ENSOCUP00000020463 | Uncharacterized protein. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.974 |
GHRL | SST | ENSOCUP00000029787 | ENSOCUP00000006540 | Uncharacterized protein. | Somatostatin. | 0.887 |
GIPR | GCG | ENSOCUP00000010218 | ENSOCUP00000019727 | Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. | Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). | 0.926 |
GIPR | GPR119 | ENSOCUP00000010218 | ENSOCUP00000010145 | Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. | G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family. | 0.581 |
GIPR | INS | ENSOCUP00000010218 | ENSOCUP00000020463 | Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. | Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. | 0.601 |
GIPR | SST | ENSOCUP00000010218 | ENSOCUP00000006540 | Gastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. | Somatostatin. | 0.435 |