NKX6-1 protein (Oryctolagus cuniculus) - STRING interaction network

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

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Score

NKX6-1

NK6 homeobox 1. (369 aa)

Predicted Functional Partners:

NEUROD1

0.698

GCG

0.684

NKX2-2

0.662

ISL1

0.645

MAFB

0.627

SST

0.623

TLE4

0.617

INS

0.610

PDX1

0.604

IRX2

0.604

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GCG	INS	ENSOCUP00000019727	ENSOCUP00000020463	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.958
GCG	IRX2	ENSOCUP00000019727	ENSOCUP00000007915	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Iroquois homeobox 2.	0.445
GCG	ISL1	ENSOCUP00000019727	ENSOCUP00000020036	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	ISL LIM homeobox 1.	0.625
GCG	MAFB	ENSOCUP00000019727	ENSOCUP00000022550	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	MAF bZIP transcription factor B.	0.699
GCG	NEUROD1	ENSOCUP00000019727	ENSOCUP00000044556	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	BHLH domain-containing protein.	0.699
GCG	NKX2-2	ENSOCUP00000019727	ENSOCUP00000019073	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	NK2 homeobox 2.	0.496
GCG	NKX6-1	ENSOCUP00000019727	ENSOCUP00000019963	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	NK6 homeobox 1.	0.684
GCG	PDX1	ENSOCUP00000019727	ENSOCUP00000004229	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Pancreatic and duodenal homeobox 1.	0.769
GCG	SST	ENSOCUP00000019727	ENSOCUP00000006540	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	Somatostatin.	0.949
INS	GCG	ENSOCUP00000020463	ENSOCUP00000019727	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	0.958
INS	ISL1	ENSOCUP00000020463	ENSOCUP00000020036	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	ISL LIM homeobox 1.	0.636
INS	MAFB	ENSOCUP00000020463	ENSOCUP00000022550	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	MAF bZIP transcription factor B.	0.686
INS	NEUROD1	ENSOCUP00000020463	ENSOCUP00000044556	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	BHLH domain-containing protein.	0.709
INS	NKX2-2	ENSOCUP00000020463	ENSOCUP00000019073	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	NK2 homeobox 2.	0.620
INS	NKX6-1	ENSOCUP00000020463	ENSOCUP00000019963	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	NK6 homeobox 1.	0.610
INS	PDX1	ENSOCUP00000020463	ENSOCUP00000004229	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Pancreatic and duodenal homeobox 1.	0.875
INS	SST	ENSOCUP00000020463	ENSOCUP00000006540	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Somatostatin.	0.943
IRX2	GCG	ENSOCUP00000007915	ENSOCUP00000019727	Iroquois homeobox 2.	Glucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity).	0.445
IRX2	ISL1	ENSOCUP00000007915	ENSOCUP00000020036	Iroquois homeobox 2.	ISL LIM homeobox 1.	0.511
IRX2	MAFB	ENSOCUP00000007915	ENSOCUP00000022550	Iroquois homeobox 2.	MAF bZIP transcription factor B.	0.543